TITLE

Antioxidant Activity of Millingtonia hortensis Linn. Stem Bark Aqueous Extract

AUTHOR(S)
M., Surendra Kumar.; N., Ravichandran.
PUB. DATE
August 2011
SOURCE
Journal of Pharmacy Research;Aug2011, Vol. 4 Issue 8, p2760
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The purpose of this work was to evaluate the antioxidant activity of aqueous extract of Millingtonia hortensis Linn (Bignoniaceae), stem bark by various methods. Both the extract and standard drug quercetin were evaluated for its antioxidant potential at 10, 20, 30, 40 and 50µg/ml. In addition, the amount of total phenol (241 µg/gm) and total flavanoid (172µg/gm) were determined. The extract showed its antioxidant potential: DPPH radical scavenging activity (IC50 29.05mg/ml), FRAP radical scavenging activity, DCF/AAPH assay (TRAP) (IC50 41.10µg/ml), ABTS radical scavenging activity (IC50 24.0µg/ml), Superoxide anion scavenging activity assay (IC50 26.0µg/ml) and Nitric oxide assay (IC50 31.0µg/ml) The present study depicts that Millingtonia hortensis Linn bark has a potent natural antioxidant that can be used as a supplementary drug for various ailments.
ACCESSION #
74455035

 

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