In-vitro comparative study of anthelmintic activity of Brassica juncea and Brassica oleracea

Lavanya, Bhaduri; S., Ramya Krishna P.; Nagarjuna, S.; Reddy, Y. Padmanabha
September 2011
Journal of Pharmacy Research;Sep2011, Vol. 4 Issue 9, p2907
Academic Journal
Brassica juncea and Brassica oleracea were easily available and commonly used in our day-to-day life. Brassica juncea is extensively used as Anthelmintic and in treatment of alopecia, epilepsy,snakebite,toothache and hiccough. Brassica oleracea is extensively used as Anthelmintic, healing of peptic ulcers, slowing down growing cancer cells. The present study aimed at the in-vitro comparative study of anthelmintic activity of aqueous and hydroalcoholic extracts of seeds of Brassica juncea and flower of Brassica oleracea. The various concentrations of the extract (100, 150, 200,300,500 mg/ml) respectively were screened for their anthelmintic activity using Pheritima posthuma. The activities were comparable with the standard drug Albendazole. When the doses of the extract is increased, a gradual increase in anthelmintic activity is observed. The study involved the determination of time of paralysis (P) and time of death (D) of the worms. In conclusion, the use of seeds of Brassica juncea and flower of Brassica oleracea as an anthelmintic have been confirmed. Hydroalcoholic extract of Brassica juncea and Brassica oleracea showed more prominent anthelmintic activity. Of these two species Brassica juncea was more efficient. Further studies are suggested to isolate the active principles responsible for the activity.


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