TITLE

STUDIU COMPARATIV AL FACTORILOR ASOCIAÅ¢I TROMBOZEI VENOASE PORTALE LA PACIENÅ¢II CIROTICI CU SAU FÄ‚RÄ‚ HEPATOCARCINOM

AUTHOR(S)
Ionescu, Mirela; Ciocîrlan, M.; Stog, V.; Diculescu, M. M.
PUB. DATE
July 2011
SOURCE
Jurnalul de Chirurgie;2011, Vol. 7 Issue 3, p401
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Portal vein thrombosis (PVT) is a dramatic complication which may appear in liver cirrhosis. Our aim was to identify the factors associated with PVT in cirrhotic patients without hepatocarcinoma (HCC) in comparison with those with liver cancer. Methods: All adult patients with liver cirrhosis and PVT recorded in the database of Elias Hospital between January 2008 and March 2010 were included. We excluded thrombhophilic disorders. HCC diagnosis was done according to Barcelona criteria. We included 42 patients with PVT, 28 patients with HCC and 14 patients without. Results: Child-Pugh class C was significantly more frequently encountered in HCC patients, 18/28 patients (64.3%) with HCC compared with 2/14 patients (14.3%) without HCC. Alanine amino-transferase(ALT), aspartic amino-transferase(AST) and gamma-glutamyl trans-peptidase(GGT) levels were significantly higher in the HCC group. A history of splenectomy and gallstones were significantly less frequently seen in HCC patients. CLIP score was quite high in our group, with a score of 4 to 6 in 67.9% of cases, with a predicted median survival of 3.2months, 0% at 2 years. Conclusion: Severity of underlying liver cirrhosis and serum enzyme levels are significantly higher in patients with cirrhosis and portal vein thrombosis associated HCC.
ACCESSION #
74263234

 

Related Articles

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics