Spectrophotometric method for the estimation of Tramadol in bulk and capsule dosage forms

Rajasekhar, K. K.; Shankarananth, V.; Jyosthna, P.; Chowdary, S. Prem Sai; Reddy, D. Purushotam
February 2011
Journal of Pharmacy Research;Feb2011, Vol. 4 Issue 2, p386
Academic Journal
A simple and sensitive spectrophotometric method has been developed for the estimation of tramadol in bulk as well as capsule dosage forms. Tramadol obeyed Beer's law in a concentration range of 10-150 μg/mL exhibiting maximum absorption at 270 nm.This met hod is extended to capsule dosage forms and there is no interference from any pharmaceutical additive and diluent. The results have been validated statistically and recovery studies confirmed the accuracy of the proposed method.


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