Clinical significance of SOX9 in human non-small cell lung cancer progression and overall patient survival

January 2012
Journal of Experimental & Clinical Cancer Research (17569966);2012, Vol. 31 Issue 1, p18
Academic Journal
The article focuses on the overall patient survival and clinical significance of high mobility groupbox 9 (SOX9) transcription factor in human non-small cell lung cancer (NSCLC) progression. The study included the methods like Western blotting, Immunohistochemical analysis and real-time reverse transcription-polymerase chain reaction (RT-PCR) to determine lung cancer cell lines, SOX9 protein and mRNA expression in normal human pneumonocytes, eight pairs of matched lung cancer tissues and their adjacent normal lung tissues. Statistical analyses were used for evaluating association between diagnosis and prognosis. It was found that SOX9 has a role in the development of the disease.


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