TITLE

In vitro Evaluation of Phototoxic Properties of Proton Pump Inhibitors, H2-receptor Antagonists and Statins

AUTHOR(S)
Gebhardt, Evi; Eberlein, Bernadette; Przybilla, Bernhard; Gilbertz, Klaus-Peter; Placzek, Marianne
PUB. DATE
March 2012
SOURCE
Acta Dermato-Venereologica;2012, Vol. 92 Issue 2, p208
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents a study which investigates the phototoxic potential of Histamine 2 receptor antagonists, proton pump inhibitors and statins utilizing a photohaemolysis test. The findings reveal that pantoprazole, esomeprazole and omeprazole exerted phototoxic effects following an exposure to ultraviolet B (UVB) radiation. Treatment with statins also entails phototoxic side-effects while ranitidine, a histamine 2 receptor antagonist induces a florid photosensitive eruption triggered by UVA.
ACCESSION #
73983677

 

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