TITLE

Optimal Threshold for Endogenous ROS Content

AUTHOR(S)
Bordin, Luciana
PUB. DATE
March 2012
SOURCE
Fertility Weekly;3/26/2012, p1
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article reports that researchers in Spain have developed optimal threshold for correct reactive oxygen species (ROS) content and a ROS-related classification of sperm. It is said that excess ROS generation is related to infertility, and apoptotic and necrotic sperm. The discussed study, conducted by researcher G. Dona and associates, analyzed the effect of altered endogenous ROS production on Tyr-phosphorylation (Tyr-P), acrosome reaction (AR), and cell viability during sperm capacitation.
ACCESSION #
73943349

 

Related Articles

  • Astaxanthin Improves Human Sperm Capacitation by Inducing Lyn Displacement and Activation. Andrisani, Alessandra; Donà, Gabriella; Tibaldi, Elena; Brunati, Anna Maria; Sabbadin, Chiara; Armanini, Decio; Alvisi, Gualtiero; Gizzo, Salvatore; Ambrosini, Guido; Ragazzi, Eugenio; Bordin, Luciana // Marine Drugs;2015, Vol. 13 Issue 9, p5533 

    Astaxanthin (Asta), a photo-protective red pigment of the carotenoid family, is known for its multiple beneficial properties. In this study, the effects of Asta on isolated human sperm were evaluated. Capacitation involves a series of transformations to let sperm acquire the correct features for...

  • MACS Improves IUI Outcome for Patients with Unexplained Infertility.  // Fertility Weekly;6/14/2010, p8 

    The article reports on the use of magnetic-activated cell sorting (MACS) which reduces the level of apoptopic markers in sperm and results in better fertilization rates for couples with unexplained infertility (UI) in a research in Taiwan. It states that MACS used for sperm preparation reduces...

  • Comparative concentrations of steroid hormones and proteins in human peri-ovulatory peritoneal and follicular fluids. Munuce, María José; Quintero, Ileena; Caille, Adriana M.; Ghersevich, Sergio; Berta, César L. // Reproductive BioMedicine Online (Reproductive Healthcare Limited;Aug2006, Vol. 13 Issue 2, p202 

    Despite the fact that both peritoneal (PF) and follicular (FF) fluids have a common ovarian origin, FF is a natural inducer of sperm acrosome reaction (AR) while PF is not. To better understand these effects, concentrations of oestradiol, progesterone and proteins in peri-ovulatory PF and FF...

  • The sensitivity of murine spermiogenesis to miglustat is a quantitative trait: a pharmacogenetic study. Bone, Wilhelm; Walden, Charlotte M.; Fritsch, Martin; Voigtmann, Ulrike; Leifke, Eckhard; Gottwald, Ulrich; Boomkamp, Stephanie; Platt, Frances M.; Van der Spoel, Aarnoud C. // Reproductive Biology & Endocrinology;2007, Vol. 5, p1 

    Background: A major event in the post-meiotic development of male germ cells is the formation of the acrosome. This process can be perturbed in C57BL/6 mice by administration of the small molecule miglustat (N-butyldeoxynojirimycin, NB-DNJ). The miglustat-treated mice produce morphologically...

  • 37° C is Optimum Temperature for Collection, Transportation, and Processing.  // Fertility Weekly;1/20/2003, p8 

    Presents a study in Ohio on the optimum temperature for collection, transportation and processing of human spermatozoa. Evaluation of sperm motility; Result of increased production of reactive oxygen species; Ranges of temperature for incubating semen samples from infertile men.

  • Relationship between sperm DNA damage, induced acrosome reaction and viability in ICSI patients. Ozmen, B.; Caglar, G. S.; Koster, F.; Schopper, B.; Diedrich, K.; Al-Hasani, S. // Reproductive BioMedicine Online (Reproductive Healthcare Limited;Aug2007, Vol. 15 Issue 2, p208 

    The DNA damage in human spermatozoa is a relevant predictor of prognosis in male infertility, whereby increased sperm DNA damage impairs the outcomes of artificial reproduction. Theoretically, DNA damage should alter the special cellular functions of human spermatozoa, and lead to diminished...

  • Src Activation Helps Regulate Capacitation and Acrosome Reaction.  // Fertility Weekly;4/13/2009, p8 

    The article reports on the study conducted by G. Varano and associates which examines the role of Src kinase in sperm activation in Italy. Phosphorylated tyrosines identify the active and active form of Src kinase during the main process of activation and reveal significant increase in...

  • The role and importance of cofilin in human sperm capacitation and the acrosome reaction. Megnagi, Bar; Finkelstein, Maya; Shabtay, Ortal; Breitbart, Haim // Cell & Tissue Research;Dec2015, Vol. 362 Issue 3, p665 

    The spermatozoon is capable of fertilizing an oocyte only after undergoing several biochemical changes in the female reproductive tract, referred to as capacitation. The capacitated spermatozoon interacts with the egg zona pellucida and undergoes the acrosome reaction, which enables its...

  • Effects of Sulfasalazine on Sperm Acrosome Reaction and Gene Expression in the Male Reproductive Organs of Rats. Fukushima, Tamio; Kato, Masashi; Adachi, Tetsuya; Hamada, Yoshimasa; Horimoto, Masao; Komiyama, Masatoshi; Mori, Chisato; Horii, Ikuo // Toxicological Sciences;May2005, Vol. 85 Issue 1, p675 

    Sulfasalazine (SASP) has been reported to depress the fertility in men and experimental male animals, but the fundamental mechanisms of infertility caused by SASP are still unknown. This study was designed to investigate the mechanisms of infertility in rats treated with SASP at a dose of 600...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics