TITLE

Phytochemical constituent, proximate analysis, antioxidant, antibacterial and wound healing properties of leaf extracts of Chromolaena Odorata

AUTHOR(S)
Anyasor, G. N.; Aina, D. A.; Olushola, M.; Aniyikaye, A. F.
PUB. DATE
April 2011
SOURCE
Annals of Biological Research;2011, Vol. 2 Issue 2, p441
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This study investigated the phytochemical constituent, proximate analysis, antioxidant, antibacterial and wound healing properties of aqueous and ethanolic leaf extracts of Chromolaena odorata (L.). Results indicated the presence of saponins, phenols and tannins in aqueous and ethanolic leaf extracts. Proximate analysis indicated that the dried leaf contained ash (10.5%), crude fat (10.75%), fiber (14.9%), moisture (15%), crude protein (18.37%) and carbohydrate (30.48%). However, aqueous extract had high antioxidant and lipid peroxide inhibitory activity while ethanolic extract showed high phenolic and hydrogen peroxide inhibitory activity at 50, 100 and 250 µg/ml respectively. Furthermore, the antibacterial studies showed that the ethanolic extract of C. odorata inhibited the growth of S. aureus, S. typhi and E. coli at various degrees while S. aureus and S. typhi only were inhibited by the aqueous extracts. However, aqueous extract (coagulation: 15.18 ± 0.023 min; clotting 0.26 ± 0.014 min) showed significantly high (p<0.05) haemostatic activity than the ethanolic extract (Coagulation: 21.0 ± 0.696 min; Clotting 2.03 ± 0.035 min). The result of these studies indicates that leaf extracts of C. odorata possess antioxidant, antibacterial and haemostatic activities which explain its folkloric use in animal nutrition and human medicine.
ACCESSION #
73897370

 

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