TITLE

Facile enantioselective synthesis of (S)-Rivastigmine and (+)-NPS-R-568 a calcimimetic agent

AUTHOR(S)
Arava, Veera Reddy.; Gorentlaa, Laxminarasimhulu.; Dubey, P. K.
PUB. DATE
February 2011
SOURCE
Der Pharma Chemica;2011, Vol. 3 Issue 1, p426
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
A practical and convenient procedure for the synthesis of enantioselective (S)-Rivastigmine and (+)-NPS-R-568 a potent calcimimetic agent is accomplished by the treatment of (S) and (R)-tertbutanesulfinamides respectively with 3-methoxyacetophenone. This protocol provides high yield and excellent enantiomeric excess in short step synthesis.
ACCESSION #
73827849

 

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