Randomized clinical trial of LigaSure versus conventional suture ligation in thyroid surgery

Schiphorst, Anandi H. W.; Twigt, Bas A.; Elias, Sjoerd G.; van Dalen, Thijs
January 2012
Head & Neck Oncology;
Background: In thyroid surgery vessel division and haemostasis make up an important and time consuming part of the operation. While the presence of the recurrent laryngeal nerve limits the liberal use of diathermia, the many arterial and venous branches to and from the thyroid gland necessitates the use of numerous conventional suture ligatures.This study evaluates the effect of using a vessel sealing system on operation time during thyroid surgery. Methods: A randomized clinical trial was performed between September 2005 and October 2008 in a teaching hospital. Forty patients undergoing total hemithyroidectomy participated in the trial. Twenty were randomized to the intraoperative use of the LigaSure Preciseâ„¢ vessel sealing system, and twenty to the use of conventional suture ligatures. Results: The total median operation time was 10 minutes shorter in the LigaSure group (56 versus 66 minutes, P = 0.001). No significant differences in complications were noticed. Conclusion: Using an electrothermal vessel sealing system during thyroid surgery is time saving. Trial registration: This trial was registered in the international standard randomized controlled trials number register (ISRCTNR) under number ISRCTNR82389535.


Related Articles

  • Has Kinesio Tape Effects on Ankle Proprioception? A Randomized Clinical Trial. Miralles, Iris; Monterde, Sònia; del Río, Olga; Valero, Sergio; Montull, Salvador; Salvat, Isabel // Clinical Kinesiology (Online Edition);Summer2014, Vol. 68 Issue 2, p9 

    Objectives: To establish whether Kinesio tape (Kt) on the ankle improves joint position sense (JPS) immediately after its application and after 48 hours wearing it. Study Design: Randomized clinical trial Setting: Motion analysis laboratory Participants: Sixty-eight volunteers randomly assigned...

  • Assessment of Recent Graduates Preparedness for Entry into Practice. Cook, Kathleen A.; Marienau, Mary Shirk; Wildgust, Bette; Gerbasi, Francis; Watkins, Judith // AANA Journal;Oct2013, Vol. 81 Issue 5, p341 

    To date no studies have been conducted to assess the preparedness of CRNA graduates for entry into practice by asking graduates and their respective employers to assess specific competencies. The purpose of this study was to assess recent graduates' preparation and performance. It was...

  • An analysis of postoperative complications and efficacy of 3-D miniplates in fixation of mandibular fractures. Gokkulakrishnan, Sadhasivam; Singh, Sanjay; Sharma, Ashish; Shahi, Ashish Kumar // Dental Research Journal;Jul2012, Vol. 9 Issue 4, p414 

    Background: Recently, various modifications in transorally placed miniplates for direct fixation of the mandibular fracture are gaining popularity. The modifications have various advantages like more rigidity, less foreign material, less time in application, etc. Among the various modifications...

  • Reduction in serum lipid parameters by incorporation of a native strain of Lactobacillus Plantarum A7 in Mice. Fazeli, Hossein; Moshtaghian, Jamal; Mirlohi, Maryam; Shirzadi, Mohamad // Iranian Journal of Diabetes & Lipid Disorders;2010, Vol. 9, p1 

    Background: Probiotics has recently been considered as an alternative biological method for chemical agents in reduction of plasma cholesterol. However, the results of human and animal studies showed various results and sometimes strain dependency and host specify of probiotic strains have...

  • The Effect of Flutamide on Ovulation Induction in PCOS Patients. Madani, Tahereh; Irani, Shohreh; Ashrafi, Mahnaz; Alsadat Nabavi, Maryam // International Journal of Fertility & Sterility;Apr-Jun2012, Vol. 6 Issue 1, p65 

    Background: Polycystic ovary syndrome (PCOS) is a disorder that affects various body organs and requires comprehensive long term evaluation and management. The aim of this study was to evaluate effect of Flutamide on ovulation induction in PCOS patients. Materials and Methods: This prospective...

  • "Split Them!" Smaller Item Sizes of Cookies Lead to a Decrease in Energy Intake in Children. Marchiori, David; Waroquier, Laurent; Klein, Olivier // Journal of Nutrition Education & Behavior;May/Jun2012, Vol. 44 Issue 3, p251 

    Objective: Examine the influence of altering the size of snack food (ie, small vs large cookies) on short- term energy intake. Methods: First- and sixth-graders (n = 77) participated in a between-subjects experimental design. All participants were offered the same gram weight of cookies during...

  • Thermal defense of extremely low gestational age newborns during resuscitation: exothermic mattresses vs polyethylene wrap. Simon, P.; Dannaway, D.; Bright, B.; Krous, L.; Wlodaver, A.; Burks, B.; Thi, C.; Milam, J.; Escobedo, M. // Journal of Perinatology;Jan2011, Vol. 31 Issue 1, p33 

    Objective:The purpose of this study was to assess the effectiveness of thermal warming mattresses compared with wrapping in a polyethylene sheet during resuscitation in extremely low gestational age newborns (ELGANs) in preventing admission hypothermia in the neonatal intensive care unit.Study...

  • Effect of acupuncture on assisted reproduction treatment outcomes. Madaschi, Camila; Braga, Daniela Paes Almeida Ferreira; Figueira, Rita de Cassia Savio; laconelli, Jr, Assumpto; com.br, edson(S>fertilitv. // Acupuncture in Medicine;Dec2010, Vol. 28 Issue 4, p180 

    Background: Acupuncture has recently been used as a complementary technique in the management of infertility. It has physiological and psychological effects and may be considered an alternative for stress reduction in women undergoing infertility treatments. Objective: To examine the hypothesis...

  • Effect of Epidural Normal Saline Bolus Prior to Catheter Removal on Parturient Sensory and Motor Function Recovery: A Pilot Study. Williams, Maria; Dodson, Tiffany; Banek, Rafal B.; Osborne, Lisa; Pellegrini, Joseph; Spence, Dennis // AANA Journal;Aug2011, Vol. 79 Issue 4, p305 

    A normal saline bolus administered before discontinuation of the epidural catheter reportedly hastens return of motor function following epidural anesthesia. However, this technique has not been investigated in parturients following vaginal delivery. In this randomized, prospective pilot study,...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics