TITLE

Immunogenicity and Tolerability of Recombinant Serogroup B Meningococcal Vaccine Administered With or Without Routine Infant Vaccinations According to Different Immunization Schedules

AUTHOR(S)
Gossger, Nicoletta; Snape, Matthew D.; Yu, Ly-Mee; Finn, Adam; Bona, Gianni; Esposito, Susanna; Principi, Nicola; Diez-Domingo, Javier; Sokal, Etienne; Becker, Birgitta; Kieninger, Dorothee; Prymula, Roman; Dull, Peter; Ypma, Ellen; Toneatto, Daniela; Kimura, Alan; Pollard, Andrew J.
PUB. DATE
February 2012
SOURCE
JAMA: Journal of the American Medical Association;2/8/2012, Vol. 307 Issue 6, p573
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents the study which determined the immunogenicity and reactogenecity of a multicomponent serogroup B Neisseria meningitidis (MenB) vaccine (4CMenB), as well as routine infant vaccines as given concomitantly or independently. The MenB vaccine is based on detergent-extracted outer membrane vesicles (OMV) with outer membrane proteins, including porin protein A. The randomized controlled study was conducted in several countries, namely, Belgium, Great Britain, Czech Republic, Germany, Italy and Spain.
ACCESSION #
71865583

 

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