TITLE

Laser-controlled Injector for Biological Applications

AUTHOR(S)
Ooie, Toshihiko; Tanaka, Masato; Nakahara, Tomonori; Yamachoshi, Yuji; Akamine, Rie; Kataoka, Masatoshi; Baba, Yoshinobu
PUB. DATE
February 2011
SOURCE
Journal of Laser Micro / Nanoengineering;2011, Vol. 6 Issue 1, p44
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
A novel injector for biological applications has been developed. It is a drop-on-demand injector driven by a pulsed laser. Explosive vapor bubbles formed on a thin metal foil, which was irradiated by laser beam, effectively ejected pure water or the biopolymer samples in water solution from a microchannel as small droplets through the port. The size and flight speed of ejected droplets were measured by CCD camera equipped with microscope and synchronized strobe light. The heat efficiency of the injector was evaluated to compare with that of conventional thermal inkjet unit. Furthermore, antigen-antibody reaction using ejected antibody solution was tested. Ejected antibody dots for procollagen type I c-peptide (P1CP) were successfully immobilized on a cyclo olefin copolymer (COC) substrate with a commercially available polymer coating. By using formed antibody dots for a sandwich ELISA the P1CP antigen was effectively detected showing that the injector is applicable for biological application such as micro immunoassay chip.
ACCESSION #
71702524

 

Related Articles

  • Measurements of sound velocity of laser-irradiated iron foils relevant to Earth core condition. Shigemori, K.; Ichinose, D.; Irifune, T.; Otani, K.; Shiota, T.; Sakaiya, T.; Azechi, H. // European Physical Journal D -- Atoms, Molecules, Clusters & Opti;Nov2007, Vol. 45 Issue 2, p301 

    We present a novel scheme to measure sound velocity of shock-compressed iron of geophysical interest. The sound velocity of laser-irradiated iron foils was obtained with side-on X-ray radiograph technique from measured rarefaction wave velocity of shocked iron. Iron foils were irradiated with a...

  • NEW PRODUCTS.  // Biologist;Mar2005, Vol. 52 Issue 1, p53 

    This article presents information on several products related to biology launched in Great Britain. By using the photosensitive area on its CCD chip more effectively, the Nikon DS-1QM digital camera is 2.5 times more efficient and 30% more sensitive than standard low light level cameras. This...

  • High spectral resolution analysis of tunable narrowband resonant grating waveguide structures. Bader, M. A.; Selle, A.; Stenzel, O.; Delmdahl, R.; Spiecker, G.; Fischer, C. // Applied Physics B: Lasers & Optics;Nov2007, Vol. 89 Issue 2/3, p151 

    A high spectral resolution analysis of narrowband reflection filters based on resonant grating waveguide structures is presented. A tunable high-performance dye laser with ∼ 0.15 cm-1 line width and a beam analyzing system consisting of three simultaneously controlled CCD cameras were used...

  • PERFORMANCE ANALYSIS OF ON-LINE CAMERA-BASED WEB INSPECTION SENSORS: A PILOT-SCALE EXPERIMENTAL STUDY. Hojjatie, B.; Lafond, E. // Georgia Journal of Science;2010, Vol. 68 Issue 4, p202 

    Camera-based web inspection sensors have been available in the paper industry for many years. However, in recent years because of a market demand for high-quality paper products, the need for realtime flaw-detection systems has increased significantly. In addition to flaw-detection capabilities,...

  • Line laser utilization in passenger tire testing. Kostial, P.; Mokrysova, M.; Klabnik, M.; Ziacik, P.; Kopal, I.; Hutyra, J. // Rubber World;Jan2006, Vol. 233 Issue 4, p18 

    The article describes the utilization of line laser in the testing of a rubber tire. A line laser is capable of copying the profile of an object and at the same it determines its width. The measuring apparatus consists of laser, CCD camera, computer and a software. It was discovered that the...

  • Size resonances in penetration of intense femtosecond laser pulses through ultra-thin foils. Bordyuh, N.; Krainov, V. // Journal of Experimental & Theoretical Physics;May2009, Vol. 108 Issue 5, p751 

    An analytic expression for the transmission coefficient as a function of the foil thickness d describing penetration of intense femtosecond laser pulses through ultra-thin foils with a thickness of the order of 30–100 nm is derived using the Vlasov-Boltzmann equation. It is found that the...

  • Images of the laser entrance hole from the static x-ray imager at NIF. Schneider, M. B.; Jones, O. S.; Meezan, N. B.; Milovich, J. L.; Town, R. P.; Alvarez, S. S.; Beeler, R. G.; Bradley, D. K.; Celeste, J. R.; Dixit, S. N.; Edwards, M. J.; Haugh, M. J.; Kalantar, D. H.; Kline, J. L.; Kyrala, G. A.; Landen, O. L.; MacGowan, B. J.; Michel, P.; Moody, J. D.; Oberhelman, S. K. // Review of Scientific Instruments;Oct2010, Vol. 81 Issue 10, p10E538 

    The static x-ray imager at the National Ignition Facility is a pinhole camera using a CCD detector to obtain images of Hohlraum wall x-ray drive illumination patterns seen through the laser entrance hole (LEH). Carefully chosen filters, combined with the CCD response, allow recording images in...

  • 3D laser blasting for biologists. Evanko, Daniel // Nature Methods;Jul2007, Vol. 4 Issue 7, p545 

    The combination of laser ablation and light sheet–based fluorescence microscopy provides researchers with a powerful way to examine function in living three-dimensional (3D) objects.

  • Pre-/During-/Post-Laser Processes to Enhance the Adhesion and Mechanical Properties of Thermal-Sprayed Coatings with a Reduced Environmental Impact. Garcia-Alonso, D.; Serres, N.; Demian, C.; Costil, S.; Langlade, C.; Coddet, C. // Journal of Thermal Spray Technology;Jun2011, Vol. 20 Issue 4, p719 

    Lasers have been used to improve the ultimate performance of thermal spray coatings for specific applications, but the full potential of additional laser treatments must be further explored. Laser treatments (auxiliary processes) can be applied before, during or after thermal spraying (main...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics