TITLE

Amyloidosis of Seminal Vesicles; Incidence and Pathologic Characteristics

AUTHOR(S)
Argon, Asuman; Şımşır, Adnan; Sarsik, Banu; Tuna, Burçin; Yörükoğlu, Kutsal; Nıflıoğlu, Gülen Gül; Şen, Sait
PUB. DATE
January 2012
SOURCE
Turkish Journal of Pathology;2012, Vol. 28 Issue 1, p44
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objective: Amyloidosis is a rare disease with various etiologies with extracellular amyloid protein depositions. At present, at least 26 distinctive amyloid forms have been detected with different clinical importance and treatment. They have characteristic staning fetaures with Congo red. Amyloid may be detected in 2-10% of prostates that have been removed because of hyperplasia or carcinoma. Amyloidosis of seminal vesicles is accepted as senil amyloidosis and it is not accompanied by systemic amyloidosis or clinical symptoms. This condition is the most common form of localized amyloidosis. In this study we aimed to investigate incidence and histologic characteristics of amyloidosis of seminal vesicles in radical prostatectomy materials of the patients whose prostate carcinomas were treated surgically. Material and Method: Amyloid depositions in seminal vesicles of 207 radical prostatectomy materials that prostates had been removed due to localized prostate carcinoma. Amyloid depositions were confirmed with Congo red staining and polarization microscope. Results: Amyloidosis of seminal vesicles was detected in 10 (4.8%) of cases. Mean age of the patients is 66.2 years. Amyloid depositions tend to be nodular and bilateral in subepithelial region of affected seminal vesicles. Amyloid depositions were not detected in blood vessels in seminal vesicles or prostate parenchyma. Conclusion: Localized amyloidosis of seminal vesicles is not an unusual finding. amyloidosis of seminal vesicles incidence in Turkish patients included in this study and histopathologic characteristics of these patients are not different from the other studies. Systemic AA amyloidosis is the most common form of amyloidosis in our country. To be aware of amyloidosis of seminal vesicles is of importance in discrimination from the other forms of amyloidosis.
ACCESSION #
70785284

 

Related Articles

  • Localized LECT2 amyloidosis of the adrenal gland with coexisting MGUS: a diagnostic challenge. Angell, Trevor; Swaika, Abhisek; Sood, Neha; Goldfarb, Melanie; Siddiqi, Imran; Ailawadhi, Sikander // Annals of Hematology;Sep2015, Vol. 94 Issue 9, p1603 

    A case study of 74-year-old woman, with a history of stage 1B uterine cancer status-post hysterectomy and radiation therapy is presented. Topics discussed include characterization of the isolated amyloid protein, confirmation of amyloid presence by Congo red staining, and role of liquid...

  • Localized amyloidosis of the gent-urinary tract. Mark, I. R.; Goodlad, J.; Lloyd-Davies, R. W. // Journal of the Royal Society of Medicine;Jun1995, Vol. 88 Issue 6, p320 

    Localized amyloidosis of the uro-genital tract is uncommon. It often simulates a neoplastic process. We describe our experience with three cases of localized amyloid of the bladder and one each of the ureter, prostate and corpora spongiosa.

  • Prevalence of histological β2-microglobulin amyloidosis in CAPD patients compared with hemodialysis patients. Jadoul, Michel; Garbar, Christian; Vanholder, Raymond; Sennesael, Jacques; Michel, Catherine; Robert, Annie; Noel, Henri; de Strihou, Charles van Ypersele // Kidney International;Sep1998, Vol. 54 Issue 3, p956 

    Examines the prevalence of histological beta2-microglobulin amyloidosis in continuous ambulatory peritoneal dialysis patients. Cause of end-stage renal failure; Use of monoclonal anti-beta2m antibody for positive immunostaining of amyloid deposits; Implication of positive Congo red staining for...

  • Treatment results of adjuvant radiotherapy and salvage radiotherapy after radical prostatectomy for prostate cancer. Wadasaki, Koichi; Kaneyasu, Yuko; Kenjo, Masahiro; Matsuura, Kanji; Murakami, Yuji; Hashimoto, Yasutoshi; Ito, Katsuhide; Kiriu, Hiroshi; Ito, Atsushi // International Journal of Clinical Oncology;Feb2007, Vol. 12 Issue 1, p37 

    The indications for and the efficacy of radiation therapy after radical operation for patients with prostate cancer are not clear. We analyzed the treatment results of adjuvant radiotherapy and salvage radiotherapy after radical prostatectomy. Between September 1997 and November 2004, 57...

  • A Novel Tool for Detecting Amyloid Deposits in Systemic Amyloidosis In Vitro and In Vivo. Ando, Yukio; Haraoka, Katsuki; Terazaki, Hisayasu; Tanoue, Yutaka; Ishikawa, Kensuke; Katsuragi, Shoichi; Nakamura, Masaaki; Xuguo Sun; Nakagawa, Kazuko; Sasamoto, Kazumi; Takesako, Kazuhiro; Ishizaki, Takashi; Sasaki, Yutaka; Doh-ura, Katsumi // Laboratory Investigation (00236837);Dec2003, Vol. 83 Issue 12, p1751 

    We synthesized (trans,trans)-1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene (BSB) and used this compound to detect amyloid fibrils in autopsy and biopsy samples from patients with localized amyloidosis, such as familial prion disease, and systemic amyloidosis, such as familial...

  • Amyloidosis--Where Are We Now and Where Are We Heading? Picken, Maria M. // Archives of Pathology & Laboratory Medicine;Apr2010, Vol. 134 Issue 4, p545 

    Context.—Amyloidoses are disorders of diverse etiology in which deposits of abnormally folded proteins share distinctive staining properties and fibrillar ultrastructural appearance. Amyloidosis ultimately leads to destruction of tissues and progressive disease. With recent advances in...

  • Role of Radical Retropubic Prostatectomy in Patients with Locally Advanced Prostate Cancer: The Influence of Gleason Score 8–10. A. Sciarra; V. Gentile; G. Voria; G. Mariotti; F. Seccareccia; A. Pastore; F. Di Silverio // Urologia Internationalis;Apr2003, Vol. 70 Issue 3, p186 

    AbstractBackground: To define whether in locally advanced prostate cancer submitted to radical retropubic prostatectomy (RRP) the presence of a Gleason score 8–10 represents an index of high risk for progression and cancer-specific death. Methods: Finally, a total of 130 men with...

  • Revisiting anatomical landmarks of cadaveric nerve-sparing radical prostatectomy in accordance to Terminologia Anatomica. Huri, Emre; Tatar, İlkan; Sargon, Mustafa Fevzi; Germiyanoğlu, Cankon; Başar, Ruhgün // Anatomy: International Journal of Experimental & Clinical Anatom;2011, Vol. 5, p18 

    Objectives: Because of the developing and standardizing urology resident education, we aimed to show important anatomical landmarks of nerve-sparing radical prostatectomy in a cadaveric dissection. Methods: The steps of the dissection were; 1) Incision of pelvic fascia, 2) Dissection of the...

  • Seminal vesicle sparing laparoscopic radical prostatectomy using a low-energy source: Better continence and potency. Shah, Shrenik J.; Goyal, Vishal; Sachar, Rajesh; Nath, Arup Kumar; Jain, Nitesh; Kapadia, Kalpesh // Indian Journal of Urology;Apr2009, Vol. 25 Issue 2, p199 

    Objectives: Ongoing with the newer developments in laparoscopic radical prostatectomy (LRP), we report our experience in a consecutive series of 42 patients with a mean 18-month follow-up. We also studied the use of a low-energy source, especially in the region of the prostatic apex and the...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics