TITLE

Angiogenesis: What's the alternative?

AUTHOR(S)
Seton-Rogers, Sarah
PUB. DATE
February 2012
SOURCE
Nature Reviews Cancer;Feb2012, Vol. 12 Issue 2, p80
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents a study that examines the role of Wilms' tumour suppressor gene (WT1)-mediated regulation of splicing factors on alternative splicing of vascular endothelial growth factor A (VEGFA). It details the method of the study in which the researchers conducted a chromatin immunoprecipitation to identify the link of WT1 and serine/arginine-rich splicing factor 1 (SRSF1). The study indicates that alternative splicing can be an alternative treatment for targeting angiogenesis.
ACCESSION #
70478618

 

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