TITLE

EPIGENETICA Y EPIGENOMA: UN PASO MAS ALLA EN LA ETIOLOGIA Y POTENCIAL TRATAMIENTO DE LAS ENFERMEDADES NEUROLOGICAS

AUTHOR(S)
GonzAlez, Sergio J.; Cristiano, Edgardo; Argibay, Pablo
PUB. DATE
August 2011
SOURCE
Medicina (Buenos Aires);2011, Vol. 71 Issue 4, p390
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The mechanisms of epigenetic regulation play an important role in the development and function of body systems. Failure in the maintenance of this regulation as well as environmental factors could contribute to the development of multiple diseases in genetically predisposed patients. Although the molecular mechanisms responsible for the etiology of most diseases are unknown, there is evidence of both genetic and environmental factors that could influence this development. Recent findings involve epigenetic mechanisms in the origin of various diseases. This review aims to describe in detail the mechanisms of epigenetic regulation and the known findings involving the dysfunction of these mechanisms as a possible cause of various diseases.
ACCESSION #
70456778

 

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