Biopsy of peripheral lymph nodes: a useful tool to diagnose opportunistic diseases in HIV-infected patients

Ramos, Carina Guedes; Goldani, Luciano Zubaran
January 2011
Tropical Doctor;Jan2011, Vol. 41 Issue 1, p26
Academic Journal
Peripheral lymphadenopathy is commonly present in HIV-infected patients and has a wide spectrum of differential diagnoses. We carried out a cross-sectional study of peripheral lymph node biopsies performed from January 2004 to December 2008 in HIV-infected patients who attended a tertiary-care hospital in southern Brazil. Only 60 of 210 peripheral lymph node biopsies performed (28%) were non-diagnostic. The most common diagnoses included: mycobacteriosis (105 cases;50.2%); lymphoma (19 cases; 9.0%); systemicmycosis (12 cases;5.7%) including histoplasmosis, cryptococcosis and histoplasmosis; and metastatic cancer (2.9%). Peripheral lymph node biopsy is a simple and useful tool to diagnose opportunistic diseases in HIV-infected patients.


Related Articles

  • The Diagnostic Results of Cervical Lymph Node FNAB Compared to Conventional Biopsy in HIV/AIDS Patients with TB Lymphadenopathy in the Bamrasnaradura Institute. Wongthawatchai, Prasong; Ruengwerayuth, Ruengsak; Chottanapund, Suthat; Siripongpreeda, Bunchorn; Boonaumnuysook, Tatep; Jarat, Wittoya // Thai Journal of Surgery;Apr-Jun2005, Vol. 26 Issue 2, p50 

    Background: Cervical lymphadenopathy is a common clinical presentation in HIV/AIDS patients at Bamrasnaradura Institute. Conventional lymph node biopsy is the standard procedure for the diagnosis of this condition but the procedure incurs a high risk for healthcare providers. Objective: To...

  • An HIV-Positive Patient with Cervical Lymphadenopathy and Skin Lesions. dos Santos, Rodrigo Pires; AndrĂ©Cartell; Goldani, Luciano Zubaran // Clinical Infectious Diseases;3/15/2007, Vol. 44 Issue 6, p884 

    The article analyzes the medical condition of an HIV-positive patient with cervical lymphadenopathy and skin lesions. Histological examination of the lymph node and skin biopsy specimen showed vascular proliferation. Dark-staining bacilli strongly suggested bacillary angiomatosis, which occurs...

  • Evaluation of Lymph Node Virus Burden in Human Immunodeficiency Virus-Infected Patients Receiving Efavirenz-Based Protease Inhibitor-Sparing Highly Active Antiretroviral Therapy. Dybul, Mark; Tae-Wook Chun; Ward, Douglas J.; Hertogs, Kurt; Larder, Brendan; Fox, Cecil H.; Orenstein, Jan M.; Baird, Barbara F.; Yuexia Li; Green, Linda G.; Engel, Delphine; Shuying Liu; Mican, JoAnn M.; Fauci, Anthony S. // Journal of Infectious Diseases;4/1/2000, Vol. 181 Issue 4 

    Examines the lymph node virus burden on human immunodeficiency viral (HIV) patients following a highly active antiretroviral therapy. Effectiveness of efavirenz-containing regimens on plasma levels suppression; Identification of replication-competent HIV low levels.

  • FNAC in the diagnosis of lymph node malignancies: A simple and sensitive tool. Wilkinson, Anne R.; Mahore, Sadhana D.; Maimoon, Sabiha A. // Indian Journal of Medical & Paediatric Oncology;Jan-Mar2012, Vol. 33 Issue 1, p21 

    Context: Fine needle aspiration cytology (FNAC) of the lymph node is a simple diagnostic tool to diagnose suspected and unsuspected secondary and primary lymph node malignancy. Aim: To study the utility of FNAC in the diagnosis of clinically suspected and unsuspected lymph node malignancy....

  • Lymph nodes cytology in HIV seropositive cases with haematological alterations. Tirumalasetti, Neelima; Latha, P. Prema // Indian Journal of Medical Research;Feb2014, Vol. 139 Issue 2, p301 

    Background & objectives: Lymphadenopathy and haematological alterations are the earliest manifestations with other associated opportunistic infections and malignancies. Hence, there is a need for simple investigations like ine needle aspiration cytology (FNAC) for evaluation of HIV...

  • Diagnostic yield of fine-needle aspiration cytology in HIV-infected patients with lymphadenopathy in the era of highly active antiretroviral therapy. Lowe, S. M.; Kocjan, G. I.; Edwards, S. G.; Miller, R. F. // International Journal of STD & AIDS;Aug2008, Vol. 19 Issue 8, p553 

    Fine-needle aspiration (FNA) cytology has an established role in the investigation of lymphadenopathy in HIV-infected patients. However, changes in the spectrum of disease have been observed since the introduction of highly active antiretroviral therapy (HAART). The aim of the study was to...

  • Sentinel lymph node mapping in early stage of endometrial and cervical cancers. Allameh, Tajossadat; Hashemi, Vahidehsadat; Mohammadizadeh, Fereshteh; Behnamfar, Fariba // Journal of Research in Medical Sciences;Feb2015, Vol. 20 Issue 2, p169 

    Background: The sentinel lymph node (SLN) is defined as the first chain node in the lymphatic basin that receives primary lymphatic flow. If the SLN is negative for metastatic disease, then other nodes are expected to be disease-free. SLN techniques have been extensively applied in the staging...

  • HIV: Getting to the bottom of CD4+ T-cell loss. Bird, Lucy // Nature Reviews Immunology;Nov2004, Vol. 4 Issue 11, p837 

    Discusses research being done on the depletion of CD4+ T cells in HIV patients. Reference to two studies by J. M. Brenchley et al, which appeared in a 2004 issue of the "Journal of Experimental Medicine," and S. Mehandru et al. in the "Journal of Experimental Medicine"; Analysis of T-cell...

  • Plasmablastic lymphoma in the ano-rectal junction presenting in an immunocompetent man: a case report.  // Journal of Medical Case Reports;2011, Vol. 5 Issue 1, p1 

    The article presents a case study of a healthy 59-year-old Caucasian man who was diagnosed with plasmablastic lymphoma in the ano-rectal junction. Plasmablastic lymphoma is common in immunocompetent patients or individuals infected with HIV, and it is generally found in oral cavity and jaw....


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics