TITLE

Diabetic Stem-Cell �Mobilopathy�

AUTHOR(S)
DiPersio, John F.
PUB. DATE
December 2011
SOURCE
New England Journal of Medicine;12/29/2011, Vol. 365 Issue 26, p2536
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses hematopoietic stem-cell (HSC) transplantation as the primary curative treatment for hematologic cancer patients. It says that the U.S. Food and Drug Administration approved the granulocyte colony-stimulating factor (G-CSF) and granulocyte macrophage colony-stimulating factor (GM-CSF) for allogeneic stem-cell mobilization, which may result in failure to mobilize enough cell numbers for transplantation. The defects in HSC mobilization after treatment are also discussed.
ACCESSION #
70209963

 

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