Evaluation of computed tomography obstruction index in guiding therapeutic decisions and monitoring percutanous catheter fragmentation in massive pulmonary embolism

Yu, Tongfu; Yuan, Mei; Zhang, Qingbo; Shi, Haibing; Wang, Dehang
November 2011
Journal of Biomedical Research;Nov2011, Vol. 25 Issue 6, p431
Academic Journal
Abstract: In the present study, we evaluated computed tomography pulmonary angiography (CTPA) in guiding therapeutic decisions and monitoring patients undergoing percutaneous catheter fragmentation in acute massive pulmonary embolism. From Jan 2003 to Dec 2009, 35 patients were diagnosed with acute massive pulmonary embolism by CTPA (T0) and treated with percutaneous catheter fragmentation. The severity was assessed by CT obstruction index (Qanadli index) and compared with Miller index. CTPA, oxygen saturation (SaO2) and pulmonary artery pressure were performed as follow-up index. The mean percentage of Qanadli index was (55±13)% (range, 40%-75%), and Miller index was (62±15)% (range, 45%-85%). Correlations between them were statistically significant (r = 0.867, P < 0.0001). The Qanadli index showed significant reduction [T0: (55±13)%; T1: (12±10)%; P < 0.001] in 33 patients. Significant correlation was observed between the Qanadli index, SaO2 (r = 0.934), and pulmonary artery pressure (r = 0.813). The Qanadli index provides an accurate method for distinguishing massive pulmonary embolism from sub-massive pulmonary embolism. It can be used to determine therapeutic options and monitor clinical outcomes.


Related Articles

  • The SOURCE Registry: what is the learning curve in trans-apical aortic valve implantation? Wendler, Olaf; Walther, Thomas; Schroefel, Holger; Lange, Rüdiger; Treede, Hendrik; Fusari, Melissa; Rubino, Paolo; Thomas, Martyn // European Journal of Cardio-Thoracic Surgery;Jun2011, Vol. 39 Issue 6, p853 

    Abstract: Objective: Trans-apical aortic valve implantation (TA-AVI) has been shown to be a reproducible technique. Early results from the SAPIEN Aortic Bioprosthesis European Outcome (SOURCE) Registry identified major access complications associated with high 30-day mortality. Using the SOURCE...

  • Percutaneous Aspiration Thrombectomy in Treatment of Massive Pulmonary Embolism. Bayiz, Hulya; Dumantepe, Mert; Teymen, Burak; Uyar, Ibrahim // Heart, Lung & Circulation;Jan2015, Vol. 24 Issue 1, p46 

    Background Pulmonary embolism (PE) associated with haemodynamic instability has exceedingly high mortality. We describe our experience using percutaneous mechanical thrombectomy (PMT) in patients with massive PE and right ventricle dysfunction. Methods Sixteen patients (11 males and five...

  • Investigating and managing suspected pulmonary embolism in an outpatient setting: the Leicester experience. Vali, Yusuf; Ladwa, Rahul; Bailie, Elaine; Bennett, Jonathan; Free, Catherine // Thorax;Mar2015, Vol. 70 Issue 3, p291 

    Having established an ambulatory service for patients with suspected and proven PE, we reviewed our outcomes. All patients referred from June 2010 to May 2012 were analysed. Of 971 patients referred, 905 underwent complete assessment (66 admitted as ineligible). 754 (77.7%) patients were...

  • Ambulating Patients with Pulmonary Artery Catheters Who Are Awaiting Heart Transplant in the Cardiac ICU. White, Joanna; Gillespie Heyman, Sarah; Harris, Mary; Sangkachand, Prasama; Parkosewich, Janet; Funk, Marjorie; Mattioli, Elisa // Dynamics;Summer2014, Vol. 25 Issue 2, p56 

    No abstract available.

  • Ambulante Behandlung von Patienten mit Lungenembolie. Steurer, Johann // Praxis (16618157);11/16/2011, Vol. 100 Issue 23, p1429 

    No abstract available.

  • Thrombolysis and pulmonary embolism. Rowbury, Gemma // British Journal of Cardiac Nursing;Feb2014, Vol. 9 Issue 2, p80 

    Acute pulmonary embolism is a condition that is associated with serious morbidity and mortality. Thrombolysis is a therapeutic option advocated by national guidelines for patients with haemodynamic compromise. However, this treatment is the subject of debate and there are a number of...

  • Hospitals face difficulty in disaster preparation.  // Medical Ethics Advisor;Jan2009, Vol. 25 Issue 1, p10 

    The article reports on the study published in the "Disaster Medicine and Public Health Preparedness" concerning U.S. hospitals' ability to manage patient care during a disaster. It found that evidence-based performance measurements are needed to evaluate hospitals' ability. According to Eliot J....

  • Monitoring the Depth of Anaesthesia. Musizza, Bojan; Ribaric, Samo // Sensors (14248220);2010, Vol. 10 Issue 12, p10896 

    One of the current challenges in medicine is monitoring the patients' depth of general anaesthesia (DGA). Accurate assessment of the depth of anaesthesia contributes to tailoring drug administration to the individual patient, thus preventing awareness or excessive anaesthetic depth and improving...

  • Concomitant coronary intervention is associated with poorer early and late clinical outcomes in selected elderly patients receiving transcatheter aortic valve implantation. Griese, Daniel P.; Reents, Wilko; Tóth, Attila; Kerber, Sebastian; Diegeler, Anno; Babin-Ebell, Jörg // European Journal of Cardio-Thoracic Surgery;Jul2014, Vol. 46 Issue 1, pe1 

    OBJECTIVES Significant coronary artery disease (CAD) is common among patients currently evaluated for transcatheter aortic valve implantation (TAVI). Limited data exist on the outcome of patients undergoing combined transcatheter treatment of aortic valve disease and CAD. The aim of the study...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics