TITLE

Reduced function CYP2C19 genotypes may increase risk for stent clots in patients receiving clopidogrel

AUTHOR(S)
Wang, Tracy Y.; Granger, Christopher B.
PUB. DATE
December 2011
SOURCE
ACP Journal Club;12/20/2011, Vol. 155 Issue 6, p12
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article focuses on the roel of cytochrome P450(CYP)2C19 variant genotypes in clinical outcomes in patients with coronary artery disease who are receiving clopidogrel. A meta-analysis of studies that evaluated reduced or increased function genetic variants of CYP2C19 and clinical outcomes in patients with angina pectoris or acute coronary syndrome is included. An increased risk for stent thrombosis was noted in these patients.
ACCESSION #
69859172

 

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