Cholinesterase inhibitors but not memantine increase syncope in older adults with mild cognitive impairment or dementia

Ng, Bradley
November 2011
ACP Journal Club;11/15/2011, Vol. 155 Issue 5, p9
Academic Journal
The article presents a study which examined whether cholinesterase inhibitors (ChEIs) or memantine increase risk for falls in older adults with mild cognitive impairment or dementia. Results showed that ChEIs increase risk for syncope but not falls and memantine reduced fracture risk but does not affect risk for falls. The need to balance the risk for adverse events with the potential benefits in individual patients is stressed.


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