Evaluation of the effect of oral ritodriné on implantation rate in in-vitro fertilization-embryo transfer cycles

Rabiee, Soghra; Farimani, Marziyyeh; Ahmadi, Maryam
July 2011
Iranian Journal of Reproductive Medicine;Summer2011, Vol. 9 Issue 3, p239
Academic Journal
Background: Pregnancy rate with IVF cycle is almost 22%. Many investigations perform to increase this rate in IVF. Various factors affect the result of IVF cycles. One of these factors could be uterine contractions that expel transferred embryo. Ritodrine is a beta mimetic agent that can block and decrease uterine contractions. Objective: The objective of this study was to determine ritodrine effectiveness for increasing the implantation rate in IVF cycles, and its probable mechanisms in decreasing uterine contractions as well. Materials and Methods: A total of 100 patients of IVF-ET cycles were divided randomly in two groups in a university hospital, Hamadan, Iran. The case group were prescribed ritodrine 10 mg / bid orally after oocyte retrieval until 10 days. The control group didn't received ridotrine. Results: In ritodrine group 14% of patients and in control group 16% had positive β-hCG test (p-value>0.5). Conclusion: Ritodrine did not improve the implantation rate in IVF-ET cycles.


Related Articles

  • Association between the proportion of dominant follicles and oocyte developmental competence. Li, Yi; Li, Rui-Qi; Ou, Song-Bang; Ren, Ling; Zhang, Ning-Feng; Wei, Li-Na; Zhang, Qing-Xue; Yang, Dong-Zi // Journal of Assisted Reproduction & Genetics;Dec2014, Vol. 31 Issue 12, p1599 

    Purpose: To explore the optimal timing for hCG triggering by investigating the impact of different proportion of dominant follicles on the oocyte developmental competence. Methods: One hundred ninety-eight infertile women were divided into three groups according to the proportion of dominant...

  • Extended in Vitro Maturation is not recommended.  // Fertility Weekly;2/14/2011, p3 

    The article presents the findings of a study conducted by U.S. researcher David E. Reichman and colleagues which examines the effects of 24-hour in vitro maturation (IVM) of cumulus-stripped immature oocytes from stimulated cycles. The study revealed that such immature oocytes give rise to...

  • Thirty-Eight Hours of hCG Priming for Immature Oocytes is Beneficial.  // Fertility Weekly;10/27/2008, p5 

    The article reports on the findings of the study by Canadian researchers, which examined whether the oocyte maturation rate after in vitro maturation (IVM) increases when the interval between human chorionic gonadotropin (hCG) priming and immature oocyte retrieval increases. Researchers found...

  • In-vitro maturation of human oocytes. Ri-Cheng Chian, Barry; Buckett, William M.; Seang-Lin Tan // Reproductive BioMedicine Online (Reproductive Healthcare Limited;Feb2004, Vol. 8 Issue 2, p148 

    Immature human oocytes can be matured and fertilized in vitro. However, subsequent embryonic development is different when the immature oocytes are retrieved in different situations. Exposure to the LH surge in vivo may be important for the oocytes to acquire the competence for maturation and...

  • Effect of adding human chorionic gonadotropin to frozen thawed embryo transfer cycles with history of thin endometrium. Davar R.; Farid Mojtahedi M.; Miraj S. // Iranian Journal of Reproductive Medicine;Apr2015 Supplement, p63 

    Introduction: Embryo implantation process is a complex phenomenon and depends on fetal and maternal factors interaction. Endometrial thickness is needed for successful implantation. Increasing endometrial thickness, raise the chance of clinical pregnancy. The triple line pattern, with thickening...

  • MicroRNA Let-7a and dicer are important in the activation and implantation of delayed implanting mouse embryos. Cheong, Ana W.Y.; Pang, Ronald T.K.; Liu, Wei-Min; Kottawatta, Kottawattage Sanda Arunika; Lee, Kai-Fai; Yeung, William S.B. // Human Reproduction;Apr2014, Vol. 29 Issue 4, p750 

    STUDY QUESTION Does Let-7a have a functional role in modulating dicer expression to activate dormant mouse blastocysts for implantation? SUMMARY ANSWER Let-7a post-transcriptionally regulates dicer expression altering microRNA expression to affect the implantation competency of the activated...

  • The strategy of group embryo culture based on pronuclear pattern on blastocyst development: a two center analysis. Restelli, Liliana; Paffoni, Alessio; Corti, Laura; Rabellotti, Elisa; Mangiarini, Alice; Viganò, Paola; Somigliana, Edgardo; Papaleo, Enrico // Journal of Assisted Reproduction & Genetics;Dec2014, Vol. 31 Issue 12, p1629 

    Purpose: To compare two embryo grouping strategies. Methods: Retrospective time-course analysis in two different centres. Two culture protocols were used at the zygote stage: 'Random Group' in which zygotes were randomly grouped and 'Definite Group' in which zygotes were grouped based on...

  • Day 3 embryo selection by metabolomic profiling of culture medium with near-infrared spectroscopy as an adjunct to morphology: a randomized controlled trial. Vergouw, Carlijn G.; Kieslinger, Dorit C.; Kostelijk, E. Hanna; Botros, Lucy L.; Schats, Roel; Hompes, Peter G.; Sakkas, Denny; Lambalk, Cornelis B. // Human Reproduction;Aug2012, Vol. 27 Issue 8, p2304 

    STUDY QUESTION Is the selection of a single Day 3 embryo by metabolomic profiling of culture medium with near-infrared (NIR) spectroscopy as an adjunct to morphology able to improve live birth rates in IVF, compared with embryo selection by morphology alone? SUMMARY ANSWER The live birth rate...

  • The impact of different time intervals between hCG priming and oocyte retrieval on ART outcomes. Ghasemian, Fatemeh; Faraji, Roya; Asgharnia, Maryam; Zahiri, Ziba; Bahadori, Mohammad Hadi // Iranian Journal of Reproductive Medicine;Jul2013, Vol. 11 Issue 7, p559 

    Background: Abnormal oocyte morphology has been associated with the hormonal environment to which the gametes are exposed. Objective: In this study, we evaluated the oocytes morphology, fertilization rate, embryos quality, and implantation rate resulted of retrieved oocytes in different times...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics