Discontinuation of thioridazine in patients with learning disabilities: balancing cardiovascular toxicity with adverse consequences of changing drugs

Davies, Simon J C; Cooke, Leila B; Moore, Alan G; Potokar, John
June 2002
BMJ: British Medical Journal (International Edition);6/22/2002, Vol. 324 Issue 7352, p1519
Academic Journal
Presents examples of the consequences of discontinuing established drugs in line with the advice of the Committee on Safety of Medicines. Topic of restrictive licensed indications for thioridazine antipsychotic drug, which was associated with prolonged QTc intervals, a marker for ventricular arrhythmias; Risk of changing drugs in patients with learning disabilities and psychiatric illness; Issue of informed consent; Suggestion that directives should allow clinicians greater flexibility in prescribing.


Related Articles

  • Bush's Medicare drug plan draws mixed reactions.  // Drug Topics;3/17/2003, Vol. 147 Issue 6, p9 

    Reports on varied reactions to U.S. President Bush's Medicare prescription drug proposal. Store chains that gave a positive rating to Bush's Medicare drug plan; Pharmacy associations' concern about a discount card program that fails to provide benefits to seniors; Choices for seniors under...

  • Tighter control of prescribing costs. Warden, John // BMJ: British Medical Journal (International Edition);6/2/90, Vol. 300 Issue 6737, p1423 

    Focuses on the public campaigns on the indicative drug budgets in Great Britain. Prescription of necessary medicines; Introduction of incentive schemes in selected areas; Monitoring of prescribing in monthly and end of year statements.

  • Thioridazine.  // AHFS Consumer Medication Information;Dec2019, p1 

    Thioridazine is used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions) in people who have already been treated with at least 2 other medications and have not been helped or who have...

  • Doctors may lose sole authority to prescribe. Warden, John // BMJ: British Medical Journal (International Edition);03/13/99, Vol. 318 Issue 7185, p690 

    Announces that legal authority to prescribe medicines in United Kingdom could be extended to professional groups other than doctors or dentists under proposals circulated by the health departments for consultation. Types of prescriber; Contact information for the report on prescription.

  • Prescribing medication in the climate of health care reform.  // Primary Care Optometry News;Jan2014, Vol. 19 Issue 1, p22 

    The article discusses the necessity for optometrists to use a more comprehensive approach in prescribing medication in relation to the reforms in healthcare policies in the U.S.

  • Belgium cuts antibiotic use by 12%. Watson, Rory // BMJ: British Medical Journal (International Edition);9/29/2001, Vol. 323 Issue 7315, p710 

    Reports that a campaign by the Belgian public health authorities has succeeded in reducing consumption of antibiotics in the country by 12 percent as of winter, 2000-2001. How the initial impact of the campaign declined as spring came; Plans for a second campaign with more explicit messages...

  • Prescribed cutback. Jaklevic, Mary Chris // Modern Healthcare;07/21/97, Vol. 27 Issue 29, p34 

    Cites the efforts of health plans to push physicians to change prescribing habits by putting them at risk for drug utilization. Average amount a physician stands to lose in the health plans; Increase in the number of health maintenance organization enrollees covered by plans that share pharmacy...

  • Can counseling reduce medication errors? Baker, Ken // Drug Topics;Apr2009, Vol. 153 Issue 4, pH10 

    The author reflects on the effectiveness of counseling in reducing medication errors as well as medical policies in guiding medical personnel through the process. He cites the report conducted by his three students and revealed that counseling could become one effective way in addressing the...

  • Budget, Medicaid cuts rip into pharmacy's pocket. Frederick, Jim // Drug Store News;3/5/2007, Vol. 29 Issue 3, p3 

    The article reports on the steep reductions in Medicaid prescription reimbursements in the U.S., to take effect on July 1, 2007. The federal government presented a 2008 budget plan in February which cuts $1.9 billion from Medicaid that covers the period of October 1 to September 30, 2008 and $13...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics