TITLE

Botox Treatment in Adductor Spasmodic Dysphonia: A Meta-Analysis

AUTHOR(S)
Boutsen, Frank; Cannito, Michael P.; Taylor, Merlin; Bender, Brenda
PUB. DATE
June 2002
SOURCE
Journal of Speech, Language & Hearing Research;Jun2002, Vol. 45 Issue 3, p469
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Over the years many studies have been conducted to document the treatment effects of Botulinum toxin type A in adductor spasmodic dysphonia. The results of these studies have led to the view that overall Botulinum toxin treatment is moderately effective. This study reviews efficacy research qualitatively and quantitatively to determine the extent to which this conclusion is fully supported by the data. Although the data indicate moderate overall improvement as a result of Botulinum toxin treatment, they also suggest significant variation across patients, measurements, and treatment conditions. This result, together with methodological limitations and lack of standardization in BT efficacy research, justifies caution when making inferences regarding BT treatment benefit in adductor spasmodic dysphonia.
ACCESSION #
6859045

 

Related Articles

  • Botox Smooths Voices.  // Current Health 2;Sep2004, Vol. 31 Issue 1, p7 

    Presents information on the use of Botox, a purified form of botulinum toxin A, against a voice disorder called spasmodic dysphonia.

  • Can Botox help ease psychogenic dysphonia? Epstein, Ruth // Pulse;10/13/2003, Vol. 63 Issue 41, p104 

    Presents question and answer on the significance of botulinum toxin in psychogenic dysphonia. Use of fibreopatic nasoendoscopy; Details of the laryngoscopic findings; Effects of injecting botulinum toxin on the condition.

  • HISTOLOGY OF NERVES AND MUSCLES IN ADDUCTOR SPASMODIC DYSPHONIA. Chhetri, Dinesh K.; Vinters, Harry V.; Blumin, Joel H.; Berke, Gerald S. // Annals of Otology, Rhinology & Laryngology;Apr2003, Vol. 112 Issue 4, p334 

    To elucidate the etiology and pathophysiology of spasmodic dysphonia, we examined the adductor branch of the recurrent laryngeal nerve and the lateral cricoarytenoid muscle from 9 consecutive patients with this disorder who were previously treated with botulinum toxin. Histologic examination...

  • Sporadic failure of botulinum toxin treatment in usually responsive patients with adductor spasmodic dysphoniaG.GalardiR.GuerrieroS.AmadioL.Leocani... Galardi, G.; Guerriero, R.; Amadio, S.; Leocani, L.; Teggi, R.; Melloni, G.; Comi, G. // Neurological Sciences;Aug2001, Vol. 22 Issue 4, p303 

    Botulinum toxin (BT) injections into vocalis (thyroarytenoid) muscle is currently considered the first-choice treatment for adductor spasmodic dysphonia, producing improvement for an average period of 3 months. In our experience, sporadic failure of BT efficacy can occur even in patients usually...

  • BOTULINUM TOXIN MANAGEMENT OF ADDUCTOR SPASMODIC DYSPHONIA AFTER FAILED RECURRENT LARYNGEAL NERVE SECTION. Sulica, Lucian; Brin, Mitchell F.; Blitzer, Andrew; Stewart, Celia F. // Annals of Otology, Rhinology & Laryngology;Jun2003, Vol. 112 Issue 6, p499 

    This study examined botulinum toxin type A (BTX-A) treatment of adductor spasmodic dysphonia patients who had previously undergone recurrent laryngeal nerve section that failed to control symptoms. Information was retrieved from records of patients treated by our group between 1984 and 1999....

  • Botulinum toxin A.  // Reactions Weekly;8/7/2010, Issue 1313, p12 

    The article describes the clinical cases of 11 patients who developed dysphonia or dysphagia following the administration of botulinum toxin A for airway compromise secondary to bilateral vocal fold motion impairment.

  • Study: Botox Shots Restore Voices, Confidence to Voice Disorder Patients; Lasting Effects Seen in Three-Year Study of People With Spasmodic Dysphonia.  // Ascribe Newswire: Medicine;4/19/2004, p76 

    Botulinum toxin type A, known as Botox, has been used off-label for years to help people with spasmodic dysphonia, a rare and often-misdiagnosed voice disorder that makes the voice sound strained, broken or breathy. In the April issue of the journal "Archives of Otolaryngology, Head and Neck...

  • Selective Denervation: Reinnervation for the Control of Adductor Spasmodic Dysphonia. Allegretto, Michael; Morrison, Murray; Rummage, Linda; Lau, David P. // Journal of Otolaryngology;May/Jun2003, Vol. 32 Issue 3, p185 

    Objectives: The objective of this study was to evaluate the efficacy of a new surgical procedure for adductor spasmodic dysphonia (AddSD). This surgery involves the bilateral selective division of the adductor branches of the recurrent laryngeal nerves with immediate reinnervation of the distal...

  • Long-Term Botulinum Toxin Dose Consistency for Treatment of Adductor Spasmodic Dysphonia. Holden, Paul K.; Yokes, David E.; Taylor, Michael B.; Till, James A.; Crumley, Roger L. // Annals of Otology, Rhinology & Laryngology;Dec2007, Vol. 116 Issue 12, p891 

    Objectives: Botulinum toxin (BTX) injection is currently the primary and most common treatment for adductor spasmodic dysphonia (ADSD). A variety of injection strategies and dosage regimens have been described. This study reports on our experience with the dosage schedule and dosing consistency...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics