Application of an Improved cDNA Competition Technique to Identify Prostate Cancer-Associated Gene
- DNA Aptamer Evolved by Cell-SELEX for Recognition of Prostate Cancer. Wang, Yuanyuan; Luo, Yun; Bing, Tao; Chen, Zheng; Lu, Minhua; Zhang, Nan; Shangguan, Dihua; Gao, Xin // PLoS ONE;Jun2014, Vol. 9 Issue 6, p1
Morbidity and mortality of prostate cancer (PCa) have increased in recent years worldwide. Currently existing methods for diagnosis and treatment do not make the situation improve, especially for hormone refractory prostate cancer (HRPC). The lack of molecular probes for PCa hindered the early...
- DNA test may help diagnose PCa, guide treatment. Schieszer, John // Urology Times;Jun2003, Vol. 31 Issue 6, p8
Describes the use of a DNA test to help diagnose and guide treatment of patients with prostate cancer. Structural changes in prostate DNA which may signal whether prostate cancer tumors have metastasized.
- Modulation of endogenous Î² -tubulin isotype expression as a result of human Î²IIIcDNA transfection into prostate carcinoma cells. Ranganathan, S; McCauley, R A; Dexter, D W; Hudes, G R // British Journal of Cancer;9/1/2001, Vol. 85 Issue 5, p735
Increases of individual Î² tubulin isotypes in antimicrotubule drug resistant cell lines have been reported by several laboratories. We have previously described elevations in Î²[SUBIII] and Î²[SUBIVa] isotypes in estramustine and paclitaxel resistant human prostate carcinoma cells. To...
- Aneuploidy and rapid cell proliferation in recurrent prostate cancers with androgen receptor gene amplification. Koivisto, P // Prostate Cancer & Prostatic Diseases;1997, Vol. 1 Issue 1, p21
Mechanisms of prostate cancer recurrence during androgen deprivation are poorly understood. We recently described androgen receptor (AR) gene amplification in 28% of recurrent prostate carcinomas from hormone-refractory prostate cancer patients. To investigate the hypothesis that amplification...
- Detection of viral HPV 16 DNA in prostate cancer and benign prostatic hyperplasia by quantitative PCR-directed analysis. Kuczyk, M; Serth, J; Machtens, S; Jonas, U // Prostate Cancer & Prostatic Diseases;2000 Supplement 1, Vol. 3 Issue 4, pS23
The human papillomavirus (HPV) seems to be involved in the pathogenesis of approximately 15% of human malignancies. However, in the past, the involvement of HPV infection in the development of prostate cancer has been controversial. Previously, highly variable frequencies ranging between 2% and...
- Epigenetics: Methylation in the driver's seat? Seton-Rogers, Sarah // Nature Reviews Cancer;Mar2013, Vol. 13 Issue 3, p149
The article discusses the study "DNA Methylation Alterations Exhibit Intraindividual Stability and Interindividual Heterogeneity in Prostate Cancer Metastases" by researcher M.J. Aryee and colleagues, which has found that epigenetic alterations can be heritable and initiate tumorigenesis.
- Down-regulation of TGF- Î² 1 production restores immunogenicity in prostate cancer cells. Matthews, E; Yang, T; Janulis, L; Goodwin, S; Kundu, S D; Karpus, W J; Lee, C // British Journal of Cancer;8/15/2000, Vol. 83 Issue 4, p519
The objective of this study is to determine if a non-immunogenic Dunning's rat prostate cancer cell line, MATLyLu, can become immunogenic by reducing the endogenous production of TGF-Î²1. An expression construct containing a DNA sequence in an antisense orientation to TGF-Î²1 (TGF-Î²1...
- Poster presentations: 2. Cytogenetics. // Journal of Medical Genetics;Sep2002 Supplement, Vol. 39, pS60
Discusses the abstract of the research paper entitled 'Genomic microarrays in the assessment of prostate cancer progression,' by Tim Lane, J. Strefford et al and presented during the British Human Genetics Conference at the University of York in England in September 2002.
- Refining cryptophyte identification with DNA-microarrays. Katja Metfies; Linda K. Medlin // Journal of Plankton Research;Dec2007, Vol. 29 Issue 12, p1071
The division Cryptophyta, Class Cryptophyceae, contains ecologically important species that are found in all kinds of aquatic habitats. The identification of the Cryptophyta is challenged by a need to examine species in the SEM or TEM to visualize features needed to identify its species. Thus,...