TITLE

Computational analysis of a novel mutation in ETFDH gene highlights its long-range effects on the FAD-binding motif

PUB. DATE
January 2011
SOURCE
BMC Structural Biology;2011, Vol. 11 Issue 1, p43
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents a study focusing on computational analysis of a novel mutation in electron transfer flavoprotein dehydrogenase (ETFDH) gene, showing its long-range effects on the flavin adenine dinucleotide (FAD) binding motif. The findings of the study show that changes made to the amino acids in ETF: ubiquinone oxidoreductase (ETF:QO) are likely to influence the FAD-binding stability.
ACCESSION #
67668867

 

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