Prolonged-release melatonin versus placebo for benzodiazepine discontinuation in patients with schizophrenia: a randomized clinical trial--the SMART trial protocol

January 2011
BMC Psychiatry;2011, Vol. 11 Issue 1, p160
Academic Journal
The article focuses on a study, which aims to assess if melatonin can facilitate the withdrawal of prolonged benzodiazepine administration in schizophrenics. It has been also investigated about the association of benzodiazepine dose reduction with clinically significant variables like sleep, psychophysiology, quality of life, and cognition.


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