Retinoblastoma in patients with regressed retinopathy of prematurity

Vasu, Usha; Nithyanandam, Suneetha; D'Souza, Sharon; Kamath, Sripathi
November 2011
Indian Journal of Ophthalmology;Nov2011, Vol. 59 Issue 6, p501
Academic Journal
Retinopathy of prematurity (ROP) is a well-known clinical entity in premature babies. We report two patients (1 and 2) with regressed ROP who later presented with retinoblastoma (RB). To the best of our knowledge, there is only one such report in the literature so far. Two unrelated patients 1 and 2, born at 32 weeks gestation were screened for ROP at 34 weeks gestation. This showed Zone II Stage II ROP which regressed by 38 weeks of gestation on follow-up. Both patients were lost to follow-up by 40 weeks of gestation. They presented at four years of age with white refl ex in the eye. Patient 1 was found to have unilateral and patient 2 bilateral RB. The occurrence of RB in these patients with regressed ROP is probably coincidental.


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