TITLE

Internamentos por infecção pelo vírus influenza A 2009 [H1N1] num hospital terciário

AUTHOR(S)
Cabral, M.; Brito, M. J.; Conde, M.; Gouveia, C.; Neves, C.; Varandas, L.; Ferreira, G. Cordeiro
PUB. DATE
May 2011
SOURCE
RPDI - Revista Portuguesa de Doenças Infecciosas;mai-ago2011, Vol. 7 Issue 2, p59
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: In Portugal the influenza A [H1NIv] pandemic emerged in October 2009. Although usually considered a benign infection, potentially serious complications may occur. In our hospital the implementation of protocols allowed the hospitalization of a minority of patients. Aims: To characterize risk/actors, complications and prognosis of patients hospitalized with H1N1v infection. Methods: Analytic study from May to December 2009. The infection was confirmed by polymerase-chain-reaction assay from nasopharyngeal aspirates. Results: A total 0/90 children [71.7% over two years-old], with a peak in November [48.9%]. No children were vaccinated and only 42,8% started oseltamivir in the first 48 hours of disease. Respiratory pathology was the most frequent [88.8%]. Complications occurred in 55.6%, 5.6% required intensive care and one died with myocarditis. Respiratory distress and atelectasis were more frequent below 2 years-old [p=0.024] [p=0.037] and with ex-prematurity [p=0.017] [p=0.041]. Bacterial coinfection occurred mainly over 2 years-old [p=0.049]. In children with asthma/ recurrent wheezing, respiratory distress [p=0.01] and hypoxemia [p=0.079] were more common. Conclusions: The association between risk/actors and complications was probably related to the type of sample. Hospitalization based on clearly defined criteria reinforces the importance that protocols may have in similar situations.
ACCESSION #
67359450

 

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