TITLE

Vitamin D and Lung Cancer

AUTHOR(S)
Rhein, Helga
PUB. DATE
December 2011
SOURCE
Current Respiratory Medicine Reviews;2011, Vol. 7 Issue 6, p440
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Lung cancer is one of the most common cancers but treatment has limited success and survival rates remain low. The active metabolite of vitamin D, 1,25-dihydroxyvitamin D, has anti-proliferative and pro-apoptotic actions in lung carcinoma cell lines in vitro. Vitamin D deficiency is associated with poor prognosis in lung cancer, and lung cancer survival varies according to vitamin D receptor genotype. Randomized controlled trials should be performed to determine whether vitamin D supplementation might have a role as an adjunct to conventional treatments for lung cancer.
ACCESSION #
67347382

Tags: LUNGS -- Tumors;  VITAMIN D;  DISEASE incidence

 

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