Determination of Major Phenolic Compounds in Echinacea spp. Raw Materials and Finished Products by High-Performance Liquid Chromatography with Ultraviolet Detection: Single-Laboratory Validation Matrix Extension

Brown, Paula N.; Chan, Michael; Paley, Lori; Betz, Joseph M.
September 2011
Journal of AOAC International;Sep/Oct2011, Vol. 94 Issue 5, p1400
Academic Journal
The article discusses a single-laboratory validation study for the determination of major phenolic compounds in Echinacea raw materials and finished products using high-performance liquid chromatography (HPLC) and ultraviolet detection. Specifically, the study was run to determine if cichoric acid, a major phenolic component of Echinacea pupurea (L.) Moench and E. angustifolia DC degrades during extraction and HPLC analysis. No significant degradation was noted over an extended testing period.


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