TITLE

Temporomandibular Disorders: A Review of Etiology, Clinical Management, and Tissue Engineering Strategies

AUTHOR(S)
Murphy, Meghan K.; MacBarb, Regina F.; Wong, Mark E.; Athanasiou, Kyriacos A.
PUB. DATE
September 2011
SOURCE
Oral & Craniofacial Tissue Engineering;2011, Vol. 1 Issue 3, p205
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Temporomandibular disorders (TMD) are a class of degenerative musculoskeletal conditions associated with morphologic and functional deformities that affect up to 25% of the population, but their etiology and progression are poorly understood and, as a result, treatment options are limited. In up to 70% of cases, TMD are accompanied by malpositioning of the temporomandibular joint (TMJ) disc, termed "internal derangement." Although the onset is not well characterized, correlations between internal derangement and osteoarthritic change have been identified. Because of the complex and unique nature of each TMD case, diagnosis requires patient-specific analysis accompanied by various diagnostic modalities. Likewise, treatment requires customized plans to address the specific characteristics of each patient's disease. In the mechanically demanding and biochemically active environment of the TMJ, therapeutic approaches that can restore joint functionality while responding to changes in the joint have become a necessity. One such approach, tissue engineering, which may be capable of integration and adaptation in the TMJ, carries significant potential for the development of repair and replacement tissues. The following review presents a synopsis of etiology, current treatment methods, and the future of tissue engineering for repairing and/or replacing diseased joint components, specifically the mandibular condyle and TMJ disc. An analysis of native tissue characterization to assist clinicians in identifying tissue engineering objectives and validation metrics for restoring healthy and functional structures of the TMJ is followed by a discussion of current trends in tissue engineering.
ACCESSION #
67127159

 

Related Articles

  • Características bucodentales de pacientes con trastornos temporomandibulares. Quinteromarmol-Juárez, Myriam; Espinosade Santillana, Irene Aurora; Martínez-Torres, Jorge; Vargas-García, Hugo Alberto // Revista Medica del IMSS;mar/abr2009, Vol. 47 Issue 2, p189 

    Objective: to describe the dental characteristics of patients with temporomandibular disorders (TMD). Methods: a survey in 130 out patients from a Clinic of Maxilofacial Surgery Service, who fulfilled the selection criteria. The social and demographic data were reported in other paper. It was...

  • Costen's syndrome.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p534 

    An encyclopedia entry for "Costen's syndrome," which refers to temporomandibular joint syndrome, is presented.

  • Posterior crossbite and temporomandibular disorders (TMDs): need for orthodontic treatment? Thilander, Birgit; Bjerklin, Krister // European Journal of Orthodontics;Dec2012, Vol. 34 Issue 6, p667 

    The aim of this work was to update the bibliography regarding the concept of ‘temporomandibular disorder (TMD)’ and ‘posterior crossbite’ and try to find out if there is any association between some special signs/symptoms of TMD and type of posterior crossbite. A...

  • Fabrication and Mechanical Characterization of Hydrogel Infused Network Silk Scaffolds. Kundanati, Lakshminath; Singh, Saket K.; Mandal, Biman B.; Murthy, Tejas G.; Gundiah, Namrata; Pugno, Nicola M. // International Journal of Molecular Sciences;Oct2016, Vol. 17 Issue 10, p1631 

    Development and characterization of porous scaffolds for tissue engineering and regenerative medicine is of great importance. In recent times, silk scaffolds were developed and successfully tested in tissue engineering and drug release applications. We developed a novel composite scaffold by...

  • Genipin Cross-Linked Fibrin Hydrogels for in vitro Human Articular Cartilage Tissue-Engineered Regeneration. Dare, Emma V.; Griffith, May; Poitras, Philippe; Kaupp, James A.; Waldman, Stephen D.; Carlsson, David J.; Dervin, Geoffrey; Mayoux, Christine; Hincke, Maxwell T. // Cells Tissues Organs;2009, Vol. 190 Issue 6, p313 

    Our objective was to examine the potential of a genipin cross-linked human fibrin hydrogel system as a scaffold for articular cartilage tissue engineering. Human articular chondrocytes were incorporated into modified human fibrin gels and evaluated for mechanical properties, cell viability, gene...

  • Possible etiological factors in temporomandibular disorders of articular origin with implications for diagnosis and treatment. Maydana, Aline Vettore; Tesch, Ricardo de Souza; Denardin, Odilon Vitor Porto; Ursi, Weber José da Silva; Dworkin, Samuel Franklin // Dental Press Journal of Orthodontics;May/Jun2010, Vol. 15 Issue 3, p78 

    Abstract The authors reviewed the factors involved in the etiology, diagnosis and treatment of temporomandibular joint disorders (TMD). Although essential, specific criteria for inclusion and exclusion in TMD diagnosis have shown limited usefulness. Currently, the Research Diagnostic Criteria...

  • PREVALENCE OF SYMPTOMS ASSOCIATED WITH TEMPOROMANDIBULAR DISORDERS IN PATIENTS WITH PSYCHOSOCIAL DISORDERS. Aditya, Amita; Lele, Shailesh; Aditya, Priyam // Journal of International Dental & Medical Research;2012, Vol. 5 Issue 1, p26 

    The identification of an unambiguous universal cause for Temporomandibular Joint Disorders (TMD) is still lacking. It is considered as a multifactorial disorder that results from existence of various contributing factors; psychosocial factors being one of them. Some studies have reported that in...

  • Análise da influência da ansiedade sobre o sinal eletromiográfico. Borini, Cynthia Bicalho; Duarte, Cláudia Lopes; Amorim, Maise Mendonça; Bérzin, Fausto // RGO: Revista Gaúcha de Odontologia;abr-jun2010, Vol. 58 Issue 2, p225 

    Objective: The objective of this study was to analyze the electromyographic activity of the superficial part of the masseter and anterior part of the temporal muscles in a non-experimental state of anxiety. Methods: The State-Trait Anxiety Inventory was used to measure anxiety. Methods: Sixteen...

  • TMJ Dysfunction Tied to Decreased Hip Range of Motion. Fischer, Michael J.; Riedlinger, Kathrin; Gutenbrunner, Christoph; Bernateck, Michael // Massage Magazine;Jun2010, Issue 169, p82 

    The article provides information on a study pertaining to the connection of temporomandibular dysfunction (TMD) and restricted range of motion (ROM) in other parts of the body for patients with complex regional pain syndrome (CRPS). The study notes that myofascial release in the jaw does not...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics