TITLE

RISK FACTORS ASSOCIATED WITH HEPATITIS C VIRUS ACQUISITION IN A TERTIARY CARE SETTING

AUTHOR(S)
Ahmed, Ibrar; Ali, Zafar; Alam, Intekhab; Nazir, Sheikh Muhammad; Taqweem, Amjad; Mahboob, Amjad
PUB. DATE
January 2011
SOURCE
Gomal Journal of Medical Sciences;Jan2011, Vol. 9 Issue 1, p32
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: Hepatitis C is prevalent worldwide. In Pakistan HCV infection has prevalence of about 4-6%. This study was conducted to identify the risk factors associated with positive hepatitis C status in a tertiary care setting. Material & Methods: This was hospital-based descriptive study, carried out in medical wards of Lady Reading Hospital, Peshawar, from June 2008 to November 2010. It included 542 anti-HCV positive patients of more than 12 years age and both sexes. Patients were selected by convenient sampling technique. Various indications for HCV testing and the risk factors for its acquisition were recorded on a pre-designed Performa. Results: Out of 542 patients, 228(42.07%) were males and 314(57.93%) females. Age ranged 14 to 90 years with mean 37.11+12.69. Re-use of syringes and therapeutic injections were reported in 433(79.88%), needle stick injuries 44(8.11%), blood transfusions 68(12.54%), dental procedures 243(44.83%), tattooing 10(1.84%), previous surgery 144(26.56%) and road traffic accidents in 16(2.95%) patients. Indications for anti-HCV testing included dilatation &/curettage in 37(11.78%), evacuation &/curettage in 41(13.05%), and antenatal checkup in 37(11.78%) female patients. Anti-HCV antibodies were detected pre-operatively in 63(11.62%), pre-endoscopy 2(0.36%), pre-vaccination against hepatitis B 14(2.58%), while donating blood in 18(3.32%), and as part of pre-employment or pre-insurance examination in 91(16.78%) patients. Conclusion: Hepatitis C is more common in patients with unnecessary use of injections, re-use of syringes, dental procedures and unscreened blood transfusions. In most of the patients, more than one risk factor can be found.
ACCESSION #
67122168

 

Related Articles

  • Correlation between an enhanced chemiluminescence assay and recombinant immunoblot assay for determining the status of HCV. Verma, Anju; Goyal, Nidhi; Bazaz, Asha; Madhik, Srikant // Asian Journal of Transfusion Science;Jan-Jun2008, Vol. 2 Issue 1, p28 

    Hepatitis C virus (HCV) accounts for one-fourth of all cases of chronic liver disease in India. It is estimated that there are 12.5 million HCV carriers in our country, and at least a quarter of them are likely to develop chronic liver disease in the next 10-15 years. Anti HCV screening among...

  • Epidemiological manifestations of hepatitis C virus genotypes and its association with potential risk factors among Libyan patients. Elasifer, Hana A.; Agnnyia, Yossif M.; Al-Alagi, Basher A.; Daw, Mohamed A. // Virology Journal;2010, Vol. 7, p317 

    Background: The information on hepatitis C virus genotypes and subtypes among Libyan population and its association with various risk factors is not known. The objectives of this study were to determine the epidemiological manifestations of HCV genotypes among Libyan patients and their...

  • Hepatitis C. Alper, Brian S.; Selius, Brian A. // Cortlandt Forum;7/25/2005, Vol. 18 Issue 7, p59 

    Presents an overview of hepatitis C. Number of people infected by hepatitis C; Etiology of hepatitis C virus; Prognosis of patient with hepatitis C virus infection.

  • Managing hepatitis C virus infection. Nash, Kathryn L.; Bentley, Ian; Hirschfield, Gideon M. // BMJ: British Medical Journal (Overseas & Retired Doctors Edition;7/4/2009, Vol. 339 Issue 7711, p37 

    The article recommends strategies for managing hepatitis C virus infection. The main mode of acquisition of hepatitis C infection in Great Britain is recreational intravenous drug use. The types of individuals that must be screened include those with unexplained abnormal liver biochemistry tests...

  • Fibrosis progression in chronic hepatitis C virus infection. McCaughan, G. W.; George, J. // Gut;Mar2004, Vol. 53 Issue 3, p318 

    Chronic hepatitis C virus infection is typically characterised by slowly progressive hepatic fibrosis. However, it is recognised that some patients do not progress while others rapidly develop significant fibrosis. Here, we review studies that have assessed factors that could influence this rate...

  • Characterization of Hepatitis C Virus genotype 3a Hypervariable region 1 in patients achieved rapid virological response to alpha interferon and Ribavirin Combination therapy. Akram, Madiha; Idrees, Muhammad; Hussain, Abrar; Afzal, Samia; Ilyas, Muhammad; Zafar, Shamail; Aftab, Mahwish; Badar, Sadaf; Khubaib, Bushra // Virology Journal;2011, Vol. 8 Issue 1, p253 

    Background: Hepatitis C virus roots a chronic liver disease. Currently approved treatment strategy includes administration of alpha interferon and ribavirin combined therapy for 24-48 weeks. One of the predictor of sustained virological response is an early virological response to treatment...

  • New Preclinical Antimalarial Drugs Potently Inhibit Hepatitis C Virus Genotype 1b RNA Replication. Ueda, Youki; Takeda, Midori; Mori, Kyoko; Dansako, Hiromichi; Wakita, Takaji; Kim, Hye-Sook; Sato, Akira; Wataya, Yusuke; Ikeda, Masanori; Kato, Nobuyuki // PLoS ONE;Aug2013, Vol. 8 Issue 8, p1 

    Background: Persistent hepatitis C virus (HCV) infection causes chronic liver diseases and is a global health problem. Although new triple therapy (pegylated-interferon, ribavirin, and telaprevir/boceprevir) has recently been started and is expected to achieve a sustained virologic response of...

  • Detection of hepatitis C virus RNA in saliva of patients with active infection not associated with periodontal or liver disease severity. Sosa-Jurado, Francisca; Hernández-Galindo, Verónica L.; Meléndez-Mena, Daniel; Mendoza-Torres, Miguel A.; Martínez-Arroniz, Fernando J.; Vallejo-Ruiz, Verónica; Reyes-Leyva, Julio; Santos-López, Gerardo // BMC Infectious Diseases;2014, Vol. 14 Issue 1, p1 

    Background Hepatitis C virus (HCV) is mainly transmitted by parenteral route, being blood transfusion and intravenous drug use the most frequent risk factors. However, it has been suggested that there are other routes of transmission. There are several studies where HCV RNA has been detected in...

  • Increase of drug use and genotype 3 in HCV-infected patients from Central West and Northeast Mexico. Muñoz-Espinosa, Linda E.; Trujillo-Trujillo, Maria E.; Martínez-Macías, Roberto F.; Panduro, Arturo; Rivas-Estilla, Ana M.; Fierro, Nora A.; Silvera-Linares, Ana L.; Torres-Valadez, Rafael; Cordero-Pérez, Paula; González-Aldaco, Karina; Chen-López, Carlos Y.; José-Abrego, Alexis; Zuñiga-Noriega, Jaime R.; Gutiérrez-Ruiz, Maria C.; Roman, Sonia // Annals of Hepatology: Official Journal of the Mexican Associatio;Sep/Oct2015, Vol. 14 Issue 5, p642 

    Background. The evolving pattern of HCV genotypes (GTs) and risk factors (RFs) in HCV-infected patients in Mexico is poorly understood. This study aimed to access the temporal trend of HCV GTs and RFs in HCV patients from two care centers. Material and methods. Chronic HCV patients [177 and 153...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics