The diagnosis and management of patients with idiopathic osteolysis

January 2011
Pediatric Rheumatology;2011, Vol. 9 Issue 1, p31
Academic Journal
The article presents an overview of diagnosis and management of idiopathic osteolysis, by discussing cases of three patients with osteolysis having different underlying pathological features. The first patient had Gorham-Stout syndrome typified by complete destruction of pelvic bones and skeletal angiomatosis. The second patient had severe non-hereditary multicentric osteolysis with bilateral destruction of the hip bones and the tarsal bones, and nephropathy. The third patient was detected with autosomal recessive Winchester syndrome due to a mutation, causing multicentric osteolysis. The article also describes the management procedures and treatments used for these patients.


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