Prediction of functionally important residues in globular proteins from unusual central distances of amino acids

January 2011
BMC Structural Biology;2011, Vol. 11 Issue 1, p34
Academic Journal
The article explains the usage of global atomic distributions to indicate functionally important residues in globular proteins. Continuous probability density functions was parameterized by describing preferred central distances of individual protein atoms. It is found that globular proteins is capable of capturing distinct orientational preferences of amino acids as resulting from different sizes, charges and hydrophobic characters of their side chains.


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