TITLE

Specificity of a whole blood IGRA in German nursing students

PUB. DATE
January 2011
SOURCE
BMC Infectious Diseases;2011, Vol. 11 Issue 1, p245
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents information on a study conducted to investigate the specificity and the negative predictive value of a whole blood interferon-gamma release assays (IGRA) in German nursing students. IGRA are used for tuberculosis (TB) screening in healthcare workers (HCWs). In the study, a group of 180 students, all with very low risk of prior TB infection, were monitored for the development of active TB disease, and IGRA was performed on them.
ACCESSION #
67058131

 

Related Articles

  • Prioritising between direct observation of therapy and case-finding interventions for tuberculosis: use of population impact measures. Heller, Richard F; Gemmell, Islay; Edwards, Richard; Buchan, Iain; Awasthi, Shally; Volmink, James A // BMC Medicine;2006, Vol. 4, p35 

    Background: Population impact measures (PIMs) have been developed as tools to help policymakers with locally relevant decisions over health risks and benefits. This involves estimating and prioritising potential benefits of interventions in specific populations. Using tuberculosis (TB) in India...

  • Treatment outcome of new culture positive pulmonary tuberculosis in Norway. Farah, Mohamed Guled; Tverdal, Aage; Steen, Tore W.; Heldal, Einar; Brantsaeter, Arne B.; Bjune, Gunnar // BMC Public Health;2005, Vol. 5 Issue 1, p14 

    Background: The key elements in tuberculosis (TB) control are to cure the individual patient, interrupt transmission of TB to others and prevent the tubercle bacilli from becoming drug resistant. Incomplete treatment may result in excretion of bacteria that may also acquire drug resistance and...

  • A systematic review of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis. Steingart, Karen R.; Henry, Megan; Laal, Suman; Hopewell, Philip C.; Ramsay, Andrew; Menzies, Dick; Cunningham, Jane; Weldingh, Karin; Pai, Madhukar // Thorax;Oct2007, Vol. 62 Issue 10, p911 

    Conventional diagnostic tests for tuberculosis have several limitations and are often unhelpful in establishing the diagnosis of extrapulmonary tuberculosis. Although commercial serological antibody based tests are available, their usefulness in the diagnosis of extrapulmonary tuberculosis is...

  • Extensively Drug-Resistant Mycobacterium tuberculosis: Charles Darwin Would Understand. Iseman, Michael D. // Clinical Infectious Diseases;12/1/2007, Vol. 45 Issue 11, p1415 

    The author reflects on the result of the study conducted by M. Pillay and colleagues which reveals the evolution of an extensively drug-resistant strain of Mycobacterium tuberculosis (XDR-TB) in the KwaZulu-Natal region of South Africa. He asserts that the discovery of XDR-TB, clinicians are...

  • Diagnosis of latent tuberculosis infection: The tuberculin skin test and interferon gamma release assays. Adeiza, Mukhtar A. // Annals of Nigerian Medicine;Jul-Dec2011, Vol. 5 Issue 2, p35 

    The author reflects on the use of tuberculin skin test (TST) and interferon gamma release assays (IGRAs) to diagnose latent tuberculosis infection (LTBI). He defines LTBI as a subclinical or asymptomatic infection with Mycobacterium tuberculosis without clinical, bacteriological, or radiological...

  • The comprehensive evaluation of latent tuberculosis infection in health care workers and of patients with active tuberculosis using TST, ELISA, and ELISPOT methods. Şımşek, Hülya; Alpar, Sibel Meryem; Aksu, Kurtuluş; Aksu, Funda; Ceyhan, İsmail; Cesur, Salih; Gözalan, Ayşegül; Ertek, Mustafa // Turkish Journal of Medical Sciences;Aug2010, Vol. 40 Issue 4, p585 

    Aim: Until recently, the tuberculin skin test (TST) has been the only assay used for detecting latent tuberculosis infection (LTBI), but two ex-vivo tests, used as alternative methods to TST, based on enumerating the M. tuberculosis-specific interferon (IFN)-γ response are now commercially...

  • Interferon beta may help to treat asthma. Bowden, Rachel // GP: General Practitioner;7/1/2005, p3 

    This article informs that according to a British research, interferon beta may help prevent or treat exacerbations of asthma that are caused by infection with a common cold virus. The researchers studied the immune response to infection with a rhinovirus in cultures of bronchial epithelial cells...

  • Cerebrospinal fluid adenosine deaminase activity: A complimentary tool in the early diagnosis of tuberculous meningitis. Kashyap, Rajpal S.; Kainthla, Rani P.; Mudaliar, Anju V.; Purohit, Hemant J.; Taori, Girdhar M.; Daginawala, Hatim F. // Cerebrospinal Fluid Research;2006, Vol. 3, p5 

    Background: Tuberculous meningitis (TBM) is the commonest form of neurotuberculosis caused by Mycobacterium tuberculosis bacilli (MTB). The diagnosis of TBM is often difficult. A reliable, costeffective and rapid diagnostic test, which can be performed in any standard pathology laboratory, could...

  • Treatment of latent tuberculosis with rifampkin is associated with higher completion rates. Nadig, V. // Thorax;Feb2007, Vol. 62 Issue 2, p167 

    The article presents a study which investigates the effectiveness of rifampicin as treatment for latent tuberculosis infection (LTBI) in the U.S. Medical records of 2,255 patients who received the treatment between January 1999 and January 2004 were reviewed. One group received isoniazid for 9...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics