TITLE

Functional characterization of the Saccharomyces cerevisiae protein Chl1 reveals the role of sister chromatid cohesion in the maintenance of spindle length during S-phase arrest

PUB. DATE
January 2011
SOURCE
BMC Genetics;2011, Vol. 12 Issue 1, p83
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents a study further characterizing the Saccharomyces cerevisiae protein Chl1 for its role in the yeast Saccharomyces cerevisiae when cells are under replication stress. The study also shows that the chl1 mutation causes growth deficiency and a mild loss in cell viability when DNA replication is arrested by hydroxyurea (HU). The study also shows that Chl1p is required for normal growth and cell viability in the presence of the replication block caused by HU.
ACCESSION #
67052743

 

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