Prevalence of cerebral white matter lesions in elderly people: a population based magnetic resonance imaging study: the Rotterdam Scan Study

January 2001
Journal of Neurology, Neurosurgery & Psychiatry;Jan2001, p2
Academic Journal
No abstract available.


Related Articles

  • Carotid atherosclerosis and cerebral white matter lesions in a population based magnetic resonance imaging study. de Leeuw, F.-E.; de Groot, J. C.; Bots, M. L.; Witteman, J. C. M.; Oudkerk, M.; Hofman, A.; van Gijn, J.; Breteler, M. M. B. // Journal of Neurology;Apr2000, Vol. 247 Issue 4, p291 

    Cerebral white matter lesions are frequently observed on magnetic resonance imaging of elderly, nondemented persons. There is evidence that white matter lesions are involved in the pathophysiology of cognitive decline and dementia. White matter lesions can be divided into those in the...

  • Silent Brain Infarcts and the Risk of Dementia and Cognitive Decline. Vermeer, Sarah E.; Prins, Niels D.; den Heijer, Tom; Hofman, Albert; Koudstaal, Peter J.; Breteler, Monique M.B. // New England Journal of Medicine;3/27/2003, Vol. 348 Issue 13, p1215 

    Background: Silent brain infarcts are frequently seen on magnetic resonance imaging (MRI) in healthy elderly people and may be associated with dementia and cognitive decline. Methods: We studied the association between silent brain infarcts and the risk of dementia and cognitive decline in 1015...

  • Severe deep white matter lesions and outcome in elderly patients with major depressive disorder:... O'Brien, John; Ames, David // BMJ: British Medical Journal (International Edition);10/10/98, Vol. 317 Issue 7164, p982 

    Presents a study examining the difference in outcome among elderly people with major depressive disorder and severe white matter lesions on magnetic resonance imaging. Risk of poor long term outcome in patients with lesions than those without lesions; Methodology of the study; Results of the study.

  • White matter changes, creatinine, age, and ankle arm index predicted incident MRI defined infarctions in older adults. Longstreth, Jr., W. T.; Dulberg, C.; Manolio, T. A. // Evidence Based Medicine;Jul2003, p121 

    The article presents a study that investigates the infarction predictors predicted by magnetic resonance imaging (MRI) scan in elderly individuals in California. Researchers conducted a cohort study on 1433 elderly people without infarctions seen on baseline scan of MRI. Moreover, they...

  • Plasma vitamin B12status and cerebral white-matter lesions. L M L de Lau // Journal of Neurology, Neurosurgery & Psychiatry;Feb2009, Vol. 80 Issue 2, p149 

    BACKGROUND AND OBJECTIVE: Elevated homocysteine has been associated with a higher prevalence of cerebral white-matter lesions and infarcts, and worse cognitive performance. This raises the question whether factors involved in homocysteine metabolism, such as vitamin B12, are also related to...

  • Silent brain infarcts and the risk of dementia and cognitive decline/Silent brain infarcts and white matter lesions increase stroke risk in the general population; the Rotterdam Scan Study.  // Current Medical Literature: Stroke Review;2003, Vol. 7 Issue 3, p82 

    Focuses on two papers from the Rotterdam Scan Study which look at the risk of dementia and stroke associated with silent cerebral infarcts and white matter hypersensitivities tested on a baseline scan. Prospective population-based study of 1077 randomly selected individuals aged 60-90 years;...

  • Abnormalities Common on Routine Brain MRI. Kemper, Carol A. // Infectious Disease Alert;Dec2007, Vol. 27 Issue 3, p35 

    The article focuses on a study which determines the prevalence of incidental asymptomatic brain findings in 2000 people undergoing brain magnetic resonance imaging (MRI). The most common findings were asymptomatic brain infarcts, asymptomatic aneurysms and benign tumors. The study found that...

  • Silent cerebral white matter lesions and cognitive function in middle-aged essential hypertensive patients. Sierra, Cristina; de la Sierra, Alejandro; Salamero, Manel; Sobrino, Javier; Gómez-Angelats, Elisenda; Coca, Antonio // American Journal of Hypertension;Jun2004, Vol. 17 Issue 6, p529 

    Background: An association between midlife blood pressure levels and late-life cognitive impairment has been reported. Hypertension is one of the most important factors related to the presence of cerebral white matter lesions, which is a prognostic factor for the development of cognitive...

  • Retinal microvascular abnormalities and subclinical magnetic resonance imaging brain infarct: a prospective study. Ning Cheung; Mosley, Thomas; Islam, Amirul; Kawasaki, Ryo; Sharrett, A. Richey; Klein, Ronald; Coker, Laura H.; Knopman, David S.; Shibata, Dean K.; Catellier, Diane; Wong, Tien Y. // Brain: A Journal of Neurology;Jul2010, Vol. 133 Issue 7, p1987 

    Silent brain infarct and white matter lesions are common radiological findings associated with the risk of clinical stroke and dementia; however, our understanding of their underlying pathophysiology and risk factors remains limited. This study aimed to determine whether assessment of retinal...

  • Incident lacunes preferentially localize to the edge of white matter hyperintensities: insights into the pathophysiology of cerebral small vessel disease. Duering, Marco; Csanadi, Endy; Gesierich, Benno; Jouvent, Eric; Hervé, Dominique; Seiler, Stephan; Belaroussi, Boubakeur; Ropele, Stefan; Schmidt, Reinhold; Chabriat, Hugues; Dichgans, Martin // Brain: A Journal of Neurology;Sep2013, Vol. 136 Issue 9, p2717 

    White matter hyperintensities and lacunes are among the most frequent abnormalities on brain magnetic resonance imaging. They are commonly related to cerebral small vessel disease and associated with both stroke and dementia. We examined the spatial relationships between incident lacunes and...


Read the Article


Sign out of this library

Other Topics