TITLE

The contribution of major risk factors and job strain to occupational class differences in coronary heart disease incidence: the MONICA Briaza and PAMELA population-based cohorts

AUTHOR(S)
Ferrario, Marco M.; Veronesi, Giovanni; Chambless, Lloyd E.; Sega, Roberto; Fornari, Carla; Bonzini, Matteo; Cesana, Giancarlo
PUB. DATE
October 2011
SOURCE
Occupational & Environmental Medicine;Oct2011, Vol. 68 Issue 10, p717
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objectives We investigated the contribution of major coronary heart disease (CHD) risk factors and job strain to occupational class differences in CHD incidence in a pooled-cohort prospective study in northern Italy. Methods 2964 men aged 25-74 from four northern Italian population-based cohorts were investigated at baseline and followed for first fatal or non-fatal CHD event (171 events). Standardised procedures were used for baseline risk factor measurements, follow-up and validation of CHD events. Four occupational classes were derived from the EriksoneGoldthorpeePortocarero social class scheme: higher and lower professionals and administrators, non-manual workers, skilled and unskilled manual workers, and the self-employed. HRs were estimated with Cox models. Results Among CHD-free subjects, with non-manual workers as the reference group, age-adjusted excess risks were found for professionals and administrators (+84%, p=0.02), the self-employed (+72%, p=0.04) and manual workers (+63%, p=0.04). The relationship was consistent across different CHD diagnostic categories. Adjusting for major risk factors only slightly reduced the reported excess risks. In a sub-sample of currently employed subjects, adjusting for major risk factors, sport physical activity and job strain reduced the excess risk for manual workers (relative change=-71.4%) but did not substantially modify the excess risks of professionals and administrators and the self-employed. Conclusions In our study, we found higher CHD incidence rates for manual workers, professionals and administrators, and the self-employed, compared to non-manual workers. When the entire spectrum of job categories is considered, the job strain model helped explain the CHD excess risk for manual workers but not for other occupational classes.
ACCESSION #
66997596

 

Related Articles

  • Variability in Systolic Blood Pressure—A Risk Factor for Coronary Heart Disease? Grove, John S.; Reed, Dwayne M.; Yano, Katsuhiko; Hwang, Lie-Ju // American Journal of Epidemiology;1997, Vol. 145 Issue 9, p771 

    Among 1, 433 men of Japanese ancestry living in Hawaii with blood pressure measured at four different physical examinations over a 10-year period, 110 events of definite coronary heart disease (CHD) occurred during 11.6 years of subsequent follow-up. Each subject's mean blood pressure, the slope...

  • Heart Disease Risk Factors Counseling and Education Programs Do Not Work.  // HealthFacts;Jan2007, Vol. 32 Issue 1, p2 

    The article discusses the ineffectiveness of multiple risk factor intervention programs in preventing heart disease. A study done by Professor Shah Ebrahim at the Cochrane Heart Group found that the advice that doctors give to reduce the risk of having a heart attack or stroke has little, if...

  • Genotypes associated with CRP elevations.  // Infectious Disease Alert;Jan2009 Primary Care, p1 

    The article discusses a study on whether the observed relationship between elevated C-reactive protein (CRP) levels and adverse cardiovascular (CV) outcomes is causal. It reports that elevated CRP levels were associated with an increased risk of ischemic heart disease but individuals evaluated...

  • Coffee does not contribute to heart disease in women.  // Modern Medicine;Jul96, Vol. 64 Issue 7, p46 

    Presents an abstract on the article `Coffee Consumption and Coronary Heart Disease in Women: A Ten-Year Follow-Up,' by W.C. Willett, M.J. Stampfer et al published in the February 14, 1996 issue of the `Journal of the American Medical Association'.

  • Hyperinsulinemia: A risk factor for ischemic heart disease in men.  // Modern Medicine;Jul96, Vol. 64 Issue 7, p51 

    Presents an abstract on the article `Hyperinsulinemia as an Independent Risk Factor for Ischemic Heart Disease,' by B. Lamarche, P. Mauriege et al published in the April 11, 1996 issue of the `New England Journal of Medicine'.

  • Still risky after sixty.  // Consumer Reports on Health;Nov96, Vol. 8 Issue 11, p129 

    Studies the link between high blood pressure, high cholesterol levels and other factors with the increased risk of coronary heart disease in middle-aged people. Results of researches conducted on the subject; Risk factors increasing heart-attack rate; Factors affecting expected life spans.

  • High homocysteine, low vitamin B6 are both risk factors for CAD.  // Geriatrics;Apr96, Vol. 51 Issue 4, p61 

    Presents an abstract of the research report `Hyperhomocysteinemia and Low Pyridoxal Phosphate: Common and Independent Reversible Risk Factors for Coronary Artery Disease,' by K. Robinson, E.L. Mayer, et al, as presented in a 1995 issue of `Circulation.'

  • Effect of habitual physical activity and physical fitness on coronary heart... Crews, Thad R. // Wellness Perspectives;Winter91, Vol. 8 Issue 2, p13 

    Reviews literature that defines the benefits of habitual physical activity and physical fitness on coronary heart disease and heart attack in middle-aged adult males. Epidemiological research supporting the hypothesis that physical inactivity and low levels of physical fitness are important...

  • Attenuated heart rate during exercise is a warning.  // Patient Care;6/15/1996, Vol. 30 Issue 11, p249 

    Presents an abstract of the report `Impaired heart rate response to graded exercise: Prognostic implications of chronotropic incompetence in the Framingham Heart Study,' by M.S. Lauer, P.M. Okin, et al, published in the 1996 edition of the `Circulation.'

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics