TITLE

Newer smallpox vaccines require new test methods

AUTHOR(S)
Traynor, Kate
PUB. DATE
November 2011
SOURCE
American Journal of Health-System Pharmacy;11/1/2011, Vol. 68 Issue 21, p2012
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article reports a public workshop held September 16, 2011 in Gaithersburg, Maryland, sponsored by the FDA and the National Institute of Allergy and Infectious Diseases (NIAID), which focused on the safety testing of smallpox vaccines. Tim Nelle, of FDA's Center for Biologics Evaluation and Research, comments on the first-generation vaccines against the variola virus. Also discussed are the fatal adverse events listed in the labeled warning for Sanofi's Acam2000, a 2nd generation vaccine.
ACCESSION #
66903936

 

Related Articles

  • Mandatory flu shots an ethical obligation.  // Hospital Infection Control & Prevention;Mar2012, Vol. 39 Issue 3, p28 

    The article presents the arguments made by bioethicist Arthur Caplan in his commentary entitled "Time to mandate influenza vaccination in health-care workers." It says that the health-care workers are obligated to honor the medical ethics requirement on the vaccination against influenza to...

  • Safety and efficacy of switching from low molecular weight heparin to dabigatran in patients undergoing elective total hip or knee replacement surgery. Wurnig, Christian; Clemens, Andreas; Rauscher, Helmuth; Kleine, Eva; Feuring, Martin; Windhager, Reinhard; Grohs, Josef // Thrombosis Journal;11/26/2015, Vol. 13, p1 

    Background: The aim of this study was to assess the safety and efficacy of switching therapy from low molecular weight heparin (LMWH; enoxaparin) to dabigatran for prevention of venous thromboembolic events (VTE) in patients undergoing elective total hip or knee replacement surgery (THR/TKR)....

  • Safety and Immunogenicity of Modified Vaccinia Ankara-Bavarian Nordic Smallpox Vaccine in Vaccinia-Naive and Experienced Human Immunodeficiency Virus-Infected Individuals: An Open-Label, Controlled Clinical Phase II Trial. Turner Overton, Edgar; Stapleton, Jack; Frank, Ian; Hassler, Shawn; Goepfert, Paul A.; Barker, David; Wagner, Eva; von Krempelhuber, Alfred; Virgin, Garth; Meyer, Thomas Peter; Müller, Jutta; Bädeker, Nicole; Grünert, Robert; Young, Philip; Rösch, Siegfried; Maclennan, Jane; Arndtz-Wiedemann, Nathaly; Chaplin, Paul // Open Forum Infectious Diseases;Spring2015, Vol. 2 Issue 2, p1 

    Background. First- and second-generation smallpox vaccines are contraindicated in individuals infected with human immunodeficiency virus (HIV). A new smallpox vaccine is needed to protect this population in the context of biodefense preparedness. The focus of this study was to compare the safety...

  • Think Small: Zebrafish as a Model System of Human Pathology. Goldsmith, J. R.; Jobin, Christian // Journal of Biomedicine & Biotechnology;2012, Vol. 2012, p1 

    Although human pathologies have mostly been modeled using higher mammal systems such as mice, the lower vertebrate zebrafish has gained tremendous attention as a model system. The advantages of zebrafish over classical vertebrate models are multifactorial and include high genetic and organ...

  • Think Small: Zebrafish as a Model System of Human Pathology. Goldsmith, J. R.; Jobin, Christian // Journal of Biomedicine & Biotechnology;2012, Vol. 2012, p1 

    Although human pathologies have mostly been modeled using higher mammal systems such as mice, the lower vertebrate zebrafish has gained tremendous attention as a model system. The advantages of zebrafish over classical vertebrate models are multifactorial and include high genetic and organ...

  • Global Advisory Committee on Vaccine Safety, 10-11 June 2015.  // Weekly Epidemiological Record;7/17/2015, Vol. 90 Issue 29, p365 

    The article discusses the 32nd Global Advisory Committee on Vaccine Safety (GACVS) meeting, clinical and scientific advisory body, that provides advice to the World Health Organization (WHO) on vaccine safety issues, that was held from June 10-11, 2015. The committee also reviewed the data...

  • Smallpox vaccine trial recruitment suspended due to myopericarditis.  // Reactions Weekly;5/8/2004, Issue 1000, p4 

    Reports on the suspension of the recruitment of volunteers into the clinical trial for ACAM2000 smallpox vaccine of Acambis plc. Reason behind the suspension; Advisory board that recommended the suspension; Plans of the company after the completion of data analysis from the clinical trial.

  • Successful switch to tenofovir after suboptimal response to entecavir in an immunocompromised patient with chronic hepatitis B and without genotypic hepatitis B virus resistance. Sarrecchia, C.; Svicher, V.; Volpi, A.; Salpini, R.; Ceccarelli, L.; Sordillo, P.; Bertoli, A.; Perno, C.; Andreoni, M. // Infection;Aug2011, Vol. 39 Issue 4, p367 

    We report a case of an immunocompromised patient affected by chronic hepatitis B virus (HBV) with high basal HBV viremia (>8 log IU/ml) who failed an entecavir regimen, despite the absence of primary or secondary drug resistance mutations. The patient achieved sustained virological success...

  • France plans overhaul of drug regulation. Benkimoun, Paul // BMJ: British Medical Journal (Overseas & Retired Doctors Edition;3/26/2011, Vol. 342 Issue 7799, p678 

    The article reports on the efforts being done by the French Ministry of Health to improve the regulation of prescription drugs in 2011.

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics