Prevention of adult asthma by early intervention during childhood: potential value of new generation immunomodulatory drugs

Holt, P. G.; Sly, P. D.
August 2000
Thorax;Aug2000, p700
Academic Journal
No abstract available.


Related Articles

  • Pharmaceutical Treatment of Asthma in Children. Carlsen, Kai-Håkon // Current Drug Targets - Inflammation & Allergy;Oct2005, Vol. 4 Issue 5, p543 

    The present review article gives an overview of the present treatment modalities of asthma during childhood and discusses the existing controversies in asthma treatment. Present guidelines of asthma treatment concentrate on treatment for adults and only marginally concern treatment of childhood...

  • Inhaled Corticosteroids in Children with Asthma. Gulliver, Tanya; Morton, Ronald; Eid, Nemr // Pediatric Drugs;2007, Vol. 9 Issue 3, p185 

    The role of inhaled corticosteroids (ICS) in the treatment of childhood asthma has been well established. An ideal corticosteroid should demonstrate high pulmonary deposition and residency time, in addition to a low systemic bioavailability and rapid systemic clearance. The lung depositions of...

  • Drug development strategies for asthma: in search of a new paradigm. Holt, Patrick G.; Sly, Peter D.; Martinez, Fernando D.; Weiss, Scott T.; Bjorkstén, Bengt; von Mutius, Erika; Wahn, Ulrich // Nature Immunology;Jul2004, Vol. 5 Issue 7, p695 

    The spiraling costs of asthma treatment seem set to continue rising, given the equivocal performance of the latest generation of specific anti-inflammatory drugs in trials in adult asthmatics. We argue that the continuation of this trend is inevitable unless there is a substantial realignment of...

  • Neuroscience, Molecular Biology, and the Childhood Roots of Health Disparities. Shonkoff, Jack P.; Boyce, W. Thomas; McEwen, Bruce S. // JAMA: Journal of the American Medical Association;6/3/2009, Vol. 301 Issue 21, p2252 

    The article explores the concept that biological and developmental disruptions occurring early in childhood cause health problems in adult life and that health promotion and interventions during childhood help prevent disease onset in adulthood. The early experiences may have a cumulative affect...

  • Improving Asthma during Pregnancy with Dietary Antioxidants: The Current Evidence. Grieger, Jessica A.; Wood, Lisa G.; Clifton, Vicki L. // Nutrients;Aug2013, Vol. 5 Issue 8, p3212 

    The complication of asthma during pregnancy is associated with a number of poor outcomes for the mother and fetus. This may be partially driven by increased oxidative stress induced by the combination of asthma and pregnancy. Asthma is a chronic inflammatory disease of the airways associated...

  • Parental influence on children's early eating environments and obesity risk: implications for prevention. Anzman, S. L.; Rollins, B. Y.; Birch, L. L. // International Journal of Obesity;Jul2010, Vol. 34 Issue 7, p1116 

    Most childhood obesity prevention efforts have focused on school-age children and adolescents and have had limited success. We argue that the first years of life, including the prenatal period, the postnatal suckling period and the transition to the modified adult diet, may provide opportunities...

  • Safety and Tolerability of an Antiasthma Herbal Formula (ASHMIâ„¢) in Adult Subjects with Asthma: A Randomized, Double-Blinded, Placebo-Controlled, Dose-Escalation Phase I Study. Kelly-Pieper, Kristin; Patil, Sangita P.; Busse, Paula; Nan Yang; Sampson, Hugh; Xiu-Min Li; Wisnivesky, Juan P.; Kattan, Meyer // Journal of Alternative & Complementary Medicine;Jul2009, Vol. 15 Issue 7, p735 

    Background: Complementary and alternative medicines are increasingly used for the treatment of asthma in Western countries. A novel three-herb antiasthma herbal medicine intervention (ASHMIâ„¢; Sino-Lion Pharmaceutical Company; Shan Dong China) was demonstrated to be effective and safe in a...

  • Prevention of malaria in pregnancy and early childhood.  // British Medical Journal (Clinical Research Edition);11/10/1984, Vol. 289 Issue 6454, p1296 

    Examines the prevention of malaria in pregnancy and early childhood in Africa and New Guinea. Consideration of antimalarial drugs for malaria; Use of proguanil during pregnancy; Effectiveness of chloroquine for malaria prophylaxis.

  • THE CHRONIC CARE MODEL: A Collaborative Approach to Preventing and Treating Asthma in Infants and Young Children. Wessel, Lois; Spain, Jacqueline // Zero to Three;Jan2005, Vol. 25 Issue 3, p20 

    Focuses on the Chronic Care Model approach to preventing and treating asthma in infants and young children. Risk factors for developing persistent asthma in children; Significance of early intervention during the early years of asthma symptoms in the reduction of the disease; Development of...

  • Parental depression and the challenge of preventing mental illness in children. Ramchandan, Paul G.; Murphy, Susannah E. // British Journal of Psychiatry;Feb2013, Vol. 202 Issue 2, p84 

    Parental depression is a risk factor for psychiatric problems in children and adolescents. Exciting scientific development have elucidated potential early mechanisms of intergenerational risk transmission and new models of intervention may help to prevent some childhood problem However, caution...


Read the Article


Sign out of this library

Other Topics