TITLE

Effect of methacholine challenge on cellular composition of sputum induction

AUTHOR(S)
Spanevello, A.; Vignola, A. M.; Bonanno, A.; Confalonieri, M.; Crimi, E.; Brusasco, V.
PUB. DATE
January 1999
SOURCE
Thorax;Jan1999, p37
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
No abstract available.
ACCESSION #
66877011

 

Related Articles

  • Failure of sputum eosinophilia after eotaxin inhalation in asthma. Bumbocea, D.; Scheerens, J.; Mann, B. S.; Stirling, R. G.; Chung, K. F. // Thorax;May2004, Vol. 59 Issue 5, p372 

    Background: Eotaxin is a chemokine specific for eosinophils and may play an important role in eosinophil recruitment in asthma. The effects of eotaxin inhalation on sputum and blood eosinophils, exhaled nitric oxide (NO), and bronchial responsiveness were determined. Methods: Eotaxin was...

  • Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects. Gauvreau, Gail M.; Boulet, Louis-Philippe; Schmid-Wirlitsch, Christine; Côté, Johanne; Duong, MyLinh; Killian, Kieran J.; Milot, Joanne; Deschesnes, Francine; Strinich, Tara; Watson, Richard M.; Bredenbröker, Dirk; O'Byrne, Paul M. // Respiratory Research;Oct2011, Vol. 12 Issue 10, p1 

    Background: Phosphodiesterase 4 (PDE4) inhibitors increase intracellular cyclic adenosine monophosphate (cAMP), leading to regulation of inflammatory cell functions. Roflumilast is a potent and targeted PDE4 inhibitor. The objective of this study was to evaluate the effects of roflumilast on...

  • Effects of Chronic Organic Dust Exposure on Respiratory Function and Airway Responsiveness in Peat Moss Factory Workers. Cormier, Yvon; Boulet, Louis-Philippe; Berube-Genest, Fernande // Archives of Environmental Health;Jan/Feb90, Vol. 45 Issue 1 

    Investigates the effects of chronic organic dust exposure on respiratory function and airway responsive in peat moss factory workers in Quebec. Measurement of bronchial responsiveness to methacholine; Prevalence of cough and sputum production in moss workers; Defense mechanisms against the...

  • Airway Function and markers of airway inflammation in patients with treated hypothyroidism. Birring, S. S.; Potel, R. B.; Parker, D.; Mckenna, S.; Hargadon, B.; Monteiro, W. R.; Falconer Smith, J. F.; Pavord, I. D. // Thorax;Mar2005, Vol. 60 Issue 3, p249 

    Background: There is increasing evidence of an association between organ specific autoimmune diseases, particularly autoimmune thyroid disease and respiratory morbidity. A study was undertaken to determine whether patients with autoimmune thyroid disease have objective evidence of airway...

  • Low-dose endotoxin inhalation in healthy volunteers - a challenge model for early clinical drug development. Janssen, Ole; Schaumann, Frank; Holz, Olaf; Lavae-Mokhtari, Bianca; Welker, Lutz; Winkler, Carla; Biller, Heike; Krug, Norbert; Hohlfeld, Jens M. // BMC Pulmonary Medicine;2013, Vol. 13 Issue 1, p1 

    Background: Inhalation of endotoxin (LPS) induces a predominantly neutrophilic airway inflammation and has been used as model to test the anti-inflammatory activity of novel drugs. In the past, a dose exceeding 15-50 μg was generally needed to induce a sufficient inflammatory response. For...

  • Airway inflammation in the elite athlete and type of sport. Belda, J.; Ricart, S.; Casan, P.; Giner, J.; Bellido-Casado, J.; Torrejon, M.; Margarit, G.; Drobnic, F. // British Journal of Sports Medicine;Apr2008, Vol. 42 Issue 4, p244 

    Background: The prevalence of asthma and bronchial hyper-responsiveness is greater in elite athletes than in the general population, and its association with mild airway inflammation has recently been reported. Objective: To study the relationship between the type of sport practised at the...

  • Induced sputum cell profiles in lung transplant recipients with or without chronic rejection: correlation with lung function. Beeh, K. M.; Kornmann, O.; Lill, J.; Buhl, R. // Thorax;Jul2001, Vol. 56 Issue 7, p557 

    Background--Sputum induction is a non- invasive procedure for measuring inflammatory processes of the lower respiratory tract. The aim of this study was to establish sputum cell counts and differentials in patients after lung transplantation (LTx), with or without chronic transplant rejection....

  • Two puffs of 90 μg albuterol prior to 3% saline sputum induction results in less FEV-1 decline than single concentration 25 mg/ml methacholine challenge. Hagan, John B.; Madaan, Arvind; Chang Keun Kim // Allergy & Asthma Proceedings;Sep/Oct2006, Vol. 27 Issue 5, p397 

    Background: Assessment of sputum eosinophilia has shown benefit in the diagnosis and monitoring of asthma. However, the possibility of bronchospasm related to the hypertonic saline used in sputum induction appears to have limited this procedure's acceptance in clinical practice. Objective:...

  • An Evaluation of Respiratory Effects Following Exposure to 2.0 ppm Formaldehyde in Asthmatics: Lung Function, Symptoms, and Airway Reactivity. Witek Jr., Theodore J.; Schachter, E. Niel; Tosun, Tarik; Beck, Gerald J.; Leaderer, Brian P. // Archives of Environmental Health;Jul/Aug87, Vol. 42 Issue 4 

    Evaluates the respiratory effects of exposure to formaldehyde in asthmatics. Absence of airway obstruction; Decrease in threshold of asthmatics in methacholine inhalation challenge test; Observation of sore throat and eye irritation during exposure.

  • Cystic fibrosis and bacterial colonization define the sputum N-glycosylation phenotype. Venkatakrishnan, Vignesh; Thaysen-Andersen, Morten; Chen, Sharon C A; Nevalainen, Helena; Packer, Nicolle H // Glycobiology;Jan2015, Vol. 25 Issue 1, p88 

    Although mucin O-glycosylation of sputum from individuals suffering from cystic fibrosis (CF) is known to be altered relative to their unaffected counterparts, protein N-glycosylation of CF sputum remains structurally and functionally under-characterized. We report the first N-glycome of soluble...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics