TITLE

Ethnic Differences in Cardiovascular Risks and Mortality in Atherothrombotic Disease: Insights From the REduction of Atherothrombosis for Continued Health (REACH) Registry

AUTHOR(S)
MEADOWS, TELLY A.; BHATT, DEEPAK L.; CANNON, CHRISTOPHER P.; GERSH, BERNARD J.; ROTHER, JOACHIM; GOTO, SHINYA; LIAU, CHIAU-SUONG; WILSON, PETER W. F.; SALETTE, GENEVIEVE; SMITH, SIDNEY C.; STEG, PH. GABRIEL
PUB. DATE
October 2011
SOURCE
Mayo Clinic Proceedings;Oct2011, Vol. 86 Issue 10, p960
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
OBJECTIVE; To determine whether ethnic-specific differences In the prevalence of cardiovascular risk factors and outcomes exist worldwide among individuals with stable arterial disease. PATIENTS AND METHODS: From December 1, 2003, to June 30, 2004, the prospective, observational REduction of Atherothrom- bosis for Continued Health (REACH) Registry enrolled 49,602 out- patients with coronary artery disease, cerebrovascular disease, and/or peripheral arterial disease from 7 predeflned ethnic/racial groups: white, Hispanic, East Asian, South Asian, Other Asian, black, and Other (comprising any race distinct from those specified). The baseline demographic and risk factor profiles, medication use, and 2-year cardiovascular outcomes were assessed among these groups. RESULTS: The prevalence of traditional atherothrombotlc risk factors varied significantly among the ethnic/racial groups. The use of medical therapies to reduce risk was comparable among all groups. At 2-year follow-up, the rate of cardiovascular death was significantly higher in blacks (6.1%) compared with all other ethnic/raclai groups (3.9%; P=.01.). Cardiovascular death rates were significantly lower In ali 3 Asian ethnic/racial groups (overall, 2.1%) compared with the other groups (4.5%; P<.O01). CONCLUSION: The REACH Registry, a large international study of individuals with atherothrombotlc disease, documents the Important ethnic-specific differences In cardiovascular risk factors and variations In cardiovascular mortality that currently exist worldwide.
ACCESSION #
66616744

 

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