Associations between polymorphism in the 2,4-Dienoyl-CoA Reductase 1 gene (DECR1) and growth traits of Shanxi White pig

Bugao Li; Xiaohong Guo; Guoqing Cao; Zhongxiao Zhou
December 2011
Animal Science Papers & Reports;2011, Vol. 29 Issue 4, p325
Academic Journal
A polymorphism within exon 2 of the 2, 4-dienoyl-CoA reductase gene (DECR1) was investigated by PCR-SSCP in 228 Shanxi White pigs. An association between the DECR1 polymorphism and growth traits in Shanxi White pigs was determined with an univariate animal model. The polymorphism was found within exon 2 of the DECR1, giving rise to genotypes AA, BB or AB. This polymorphism exhibited a significant effect of generation and sex (P<0.05, P<0.01) on growth traits and backfat thickness. At the age of six months BB pigs showed the body weight and chest girth higher than AA and AB animals. However, the polymorphism revealed no significant effects on other growth traits (P>0.05) though a trend of BB>AB>AA was showed.


Related Articles

  • Two alternative exons can result from activation of the cryptic splice acceptor site deep within intron 2 of the dystrophin gene in a patient with as yet asymptomatic dystrophinopathy. Yagi, Mariko; Takeshima, Yasuhiro; Wada, Hiroko; Nakamura, Hajime; Matsuo, Masafumi // Human Genetics;Feb2003, Vol. 112 Issue 2, p164 

    Intron 2 of the dystrophin gene is unusually large, extending 157 kb on the X-chromosome, and is known to contain one cryptic exon 2a. Here, we report that a single nucleotide change in the middle of this huge intron is a source of two novel extra exons. A novel point mutation changing T to A...

  • Assessment of the CTNNA3 gene encoding human αT-catenin regarding its involvement in dilated cardiomyopathy. Janssens, Barbara; Mohapatra, Bhagyalaxmi; Vatta, Matteo; Goossens, Steven; Vanpoucke, Griet; Kools, Patrick; Montoye, Tony; van Hengel, Jolanda; Bowles, Neil E.; van Roy, Frans; Towbin, Jeffrey A. // Human Genetics;Mar2003, Vol. 112 Issue 3, p227 

    αT-catenin is a novel member of the α-catenin family, which shows most abundant expression in cardiomyocytes and in peritubular myoid cells of the testis, pointing to a specific function for αT-catenin in particular muscle tissues. Like other α-catenins, αT-catenin provides an...

  • Using ESTs to improve the accuracy of de novo gene prediction. Chaochun Wei; Brent, Michael R // BMC Bioinformatics;2006, Vol. 7, p1 

    Background: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Gene prediction systems based exclusively on EST alignments miss these exons and genes, leading to poor sensitivity. De...

  • Duplication of the MID1 first exon in a patient with Opitz G/BBB syndrome. Winter, Jennifer; Lehmann, Tanja; Suckow, Vanessa; Kijas, Zofia; Kulozik, Andreas; Kalscheuer, Vera; Hamel, Ben; Devriendt, Koen; Opitz, John; Lenzner, Steffen; Ropers, Hans-Hilger; Schweiger, Susann // Human Genetics;Mar2003, Vol. 112 Issue 3, p249 

    Opitz G/BBB syndrome is a malformation syndrome of the ventral midline mainly characterized by hypertelorism, swallowing difficulties, hypospadias and developmental delay. SSCP analysis and genomic sequencing of the MID1 open reading frame have identified mutations in 80% of the families with...

  • When new exons are born. Sorek, R. // Heredity;Oct2009, Vol. 103 Issue 4, p279 

    In this article the author reflects on the common beliefs prior to the genomic era known as the new exons. He explains that there are thousands of new exons that are alternately spliced into human transcripts. The author also examines the elements of Alu, which is a primate-specific...

  • De Novo Exon Duplication in a New Allele of Mouse Glira1 (Spasmodic). Holland, Katherine D.; Fleming, Michelle T.; Cheek, Susannah; Moran, Jennifer L.; Beier, David R.; Meisler, Miriam H. // Genetics;Dec2006, Vol. 174 Issue 4, p2245 

    The novel neurological mutant Cincinatti arose by genomic duplication of exon 5 in the glycine receptor gene Glra1. The mutant transcript results in premature protein truncation. A direct repeat of the pentamer GGGGC is present adjacent to the breakpoints and may have mediated the duplication...

  • exon.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p827 

    An encyclopedia entry for "exon" is presented.

  • Exon/intron boundaries, novel polymorphisms, and association analysis with schizophrenia of the human synaptic vesicle monoamine transporter (SVMT) gene. Kunugi, H.; Ishida, S.; Akahane, A.; Nanko, S. // Molecular Psychiatry;2001, Vol. 6 Issue 4, p456 

    The synaptic vesicular monoamine transporter (SVMT), alternatively vesicular monoamine transporter 2 (VMAT2), pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Altered functions of SVMT have been implicated in the pathogensis of...

  • Regulation of ATP Citrate-Lyase Gene Expression in Hepatocytes and Adipocytes in Normal and Genetically Obese Rats1. Fukuda, Hitomi; Iritani, Nobuko // Journal of Biochemistry;1999, Vol. 126 Issue 2, p437 

    Transcriptional regulation of ATP citrate-lyase (ACL, one of the lipogenic enzymes) gene by glucose/insulin, polyunsaturated fatty acid (PUFA), and leptin has been investigated in hepatocytes and adipocytes of obese Wistar fatty rats and their lean littermates. The sequence spanning nucleotides...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics