TITLE

No effect of the α1-antichymotrypsin A allele in Alzheimer's disease

AUTHOR(S)
Didierjean, O.; Martinez, M.; Campion, D.; Hannequin, D.; Dubois, B.; Martin, C.; Puel, M.; Anterion, C. Thomas; Pasquier, F.; Moreau, O.; Babron, M. C.; Penet, C.; Agid, Y.; Clerget-Darpoux, F.; Frebourg, T.; Brice, A.
PUB. DATE
July 1997
SOURCE
Journal of Neurology, Neurosurgery & Psychiatry;Jul1997, Vol. 63 Issue 1, p103
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
No abstract available.
ACCESSION #
66299251

 

Related Articles

  • Dementia.  // Current Medical Literature: Neurology;2007, Vol. 23 Issue 1, p17 

    The article presents abstracts of medical research on dementia. They include "Alpha 1-Antichymotrypsin, An Inflammatory Protein Overexpressed in Alzheimer's Disease Brain, Induces Tau Phosphorylation in Neurons," "Genetic Variation in the Choline Acetyltransferase Gene May Be Associated With the...

  • Editorial: Drug Targets in Ageing and Age-Associated Diseases. Caruso, Calogero; Jirillo, Emilio // Current Pharmaceutical Design;9/11/2008, Vol. 14 Issue 26, p2635 

    The article discusses various reports published within the issue, including one on the state of the art of anti-aging therapies and the role of a-1-anti-chymotrypsin (ACT) in Alzheimer's disease (AD).

  • Apolipoprotein E and α1-antichymotrypsin in dialysis-related amyloidosis. Gejyo, Fumitake; Kimura, Hideki; Suzuki, Satoru; Miyazaki, Ryoichi; Naiki, Hironobu; Nakakuki, Kazuya // Kidney International Supplement;Nov1997, Issue 62, pS-75 

    Dialysis-re lilted amyloidosis ;ts represented by carpal tunnel syndrome is a serious complication of long-term dialysis treatment of patients with chronic renal failure. β2-microglobulin has been identified as a structural component of the amyloid deposits, but other factors also are...

  • Apolipoprotein E and α1-antichymotrypsin in dialysis-related amyloidosis. Gejyo, Fumitake; Kimura, Hideki; Suzuki, Satoru; Miyazaki, Ryoichi; Naiki, Hironobu; Nakakuki, Kazuya // Kidney International Supplement;Nov1997, Issue 62, pS75 

    Dialysis-re lilted amyloidosis ;ts represented by carpal tunnel syndrome is a serious complication of long-term dialysis treatment of patients with chronic renal failure. β2-microglobulin has been identified as a structural component of the amyloid deposits, but other factors also are...

  • The Association of ACT -17 A/T Polymorphism with Alzheimer's Disease: A Meta-Analysis. Chao Dou; Jiyuan Zhang; Yang Sun; Xin Zhao; Qihan Wu; Chaoneng Ji; Shaohua Gu; Yi Xie; Yumin Mao // Current Alzheimer Research;Jan2013, Vol. 10 Issue 1, p63 

    Association studies between Alpha-1-antichymotrypsin (ACT)-17(A > T) polymorphisms and Alzheimer's disease (AD) susceptibility have shown conflicting results. In this investigation, we performed a meta-analysis to assess the purported associations. Subgroup analyses based on ethnicity...

  • Amyloid-associated proteins alpha1-antichymotrypsin and apolipoprotein in E promote assembly of... Ma, Jianyi; Yee, Ann // Nature;11/3/1994, Vol. 372 Issue 6501, p92 

    Reports that the protease inhibitor alpha1-antichymotrypsin and the lipid transport apolipoprotein E (apoE) serve strong stimulatory roles in the polymerization 42-amino-acid beta-peptide (Abeta) into amyloid filaments of Alzheimer's disease. Experiments.

  • Alzheimer's disease: Genetic combinations multiply risk of dementia.  // Geriatrics;Sep95, Vol. 50 Issue 9, p14 

    Reports on University of Pittsburgh Medical Center, Pennsylvania researchers' discovery of a genetic link for Alzheimer's disease (AD). Conclusion that two forms of a gene for alpha-antichymotrypsin (ACT) can greatly affect an individual's risk of developing late-onset AD; Genetic findings on...

  • Alzheimer's gene `the most important ever found'. Miller, Susan Katz // New Scientist;8/21/93, Vol. 139 Issue 1887, p17 

    Reports on the significance of the link between an apolipoprotein E (ApoE) allele and the genes associated with Alzheimer's disease. Research by genetic epidemiologist in the Allen Roses Laboratory; Indicator of an increased risk of developing the disease; Gene dose effect.

  • Polymorphism in the alpha1-antichymotrypsin (ACT) gene promoter: effect on expression in transfected glial and liver cell lines and plasma ACT concentrations. Morgan, Kevin; Licastro, Federico; Tilley, Louise; Ritchie, Alistair; Morgan, Linda; Pedrini, Steve; Kalsheker, Noor // Human Genetics;Sep2001, Vol. 109 Issue 3, p303 

    Alpha1-antichymotrypsin (ACT: new identification SERPINA3) is a member of the serine proteinase inhibitor (serpin) gene family and biochemically has been shown to be a constituent of the senile plaques of Alzheimer's disease. We describe a polymorphism (G→T) in the promoter region of the...

  • Risk and protective effects of the APOE gene towards Alzheimer's disease in the Kungsholmen project: variation by age and sex. Qiu, C.; Kivipelto, M.; Agüero-Torres, H.; Winblad, B.; Fratiglioni, I.; Agüero-Torres, H; Fratiglioni, L // Journal of Neurology, Neurosurgery & Psychiatry;Jun2004, Vol. 75 Issue 6, p828 

    Background: The risk effect of APOE epsilon 4 allele for Alzheimer's disease is acknowledged, whereas the putative protective effect of epsilon 2 allele remains in debate.Objectives: To investigate whether those inconsistent findings may be attributable to differences...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics