TITLE

Anticytokine approaches in pulmonary fibrosis: bringing factors into focus

AUTHOR(S)
Coker, R. K.; Laurent, G. J.
PUB. DATE
March 1997
SOURCE
Thorax;Mar1997, Vol. 52 Issue 3, p294
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
No abstract available.
ACCESSION #
66296728

 

Related Articles

  • Idiopathic Pulmonary Fibrosis.  // Annals of Internal Medicine;Dec76, Vol. 85 Issue 6, p769 

    Focuses on a conference on idiopathic pulmonary fibrosis held by the National Institutes of Health in Bethesda, Maryland on November 13, 1975. Discussion on the clinical aspects of idiopathic pulmonary fibrosis; Information on histologic observations in relation to idiopathic pulmonary...

  • Integrin-linked kinase (ILK) in pulmonary fibrosis. Kavvadas, Panagiotis; Kypreou, Katerina; Protopapadakis, Evdokia; Prodromidi, Evangelia; Sideras, Paschalis; Charonis, Aristidis; Kypreou, Katerina P; Charonis, Aristidis S // Virchows Archiv;Nov2010, Vol. 457 Issue 5, p563 

    Pulmonary fibrosis is a common feature of a large group of lung diseases. The molecular mechanisms underlying pulmonary fibrosis and the key macromolecules involved are not fully understood yet. In an effort to better understand aspects of pulmonary fibrosis, the established bleomycin injection...

  • Role of Cytokines and Cytokine Therapy in Wound Healing and Fibrotic Diseases. Gharaee-Kermani, Mehrnaz; Phan, Sem H. // Current Pharmaceutical Design;Jul2001, Vol. 7 Issue 11, p1083 

    Cytokines are critical to a myriad of fundamental homeostatic and pathophysiological processes such as fever, wound healing, inflammation, tissue repair and fibrosis. They play important roles in regulating cell function such as proliferation, migration, and matrix synthesis. It is the balance...

  • Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis. Piguet, P.F.; Collart, M.A. // Nature;3/15/1990, Vol. 344 Issue 6263, p245 

    Demonstrates that tumor necrosis factor plays an important part in silica-induced pulmonary fibrosis in mice. Methods; Results; Discussion.

  • VEGF levels in pulmonary fibrosis. Richter, A. G.; Maughan, E. O.; Perkins, G. D.; Nathani, N.; Thickett, D. R. // Thorax;Feb2005, Vol. 60 Issue 2, p171 

    Presents letter to the editor about vascular endothelial growth factor level in pulmonary fibrosis.

  • Localisation of transforming growth factor β1 and β3 mRNA transcripts in normal and fibrotic human lung. Coker, R. K.; Laurent, G. J.; Jeffery, P. K.; du Bois, R. M.; Black, C. M.; McAnulty, R. J. // Thorax;Jul2001, Vol. 56 Issue 7, p549 

    Background--Transforming growth factor β1 is implicated in the pathogenesis of lung fibrosis. It promotes extracellular matrix accumulation by increasing procollagen synthesis and reducing degradation. TGFβ1 gene and protein expression increase in experimental lung fibrosis, and TGFβ1...

  • Recent Advances in Molecular Targets and Treatment of Idiopathic Pulmonary Fibrosis: Focus on TGFβ Signaling and the Myofibroblast. Gharaee-Kermani, M.; Hu, B.; Phan, S. H.; Gyetko, M. R. // Current Medicinal Chemistry;Apr2009, Vol. 16 Issue 11, p1400 

    Idiopathic Pulmonary Fibrosis (IPF) is characterized by injury and loss of lung epithelial cells, accumulation of fibroblasts/myofibroblasts and abnormal remodeling of the lung parenchyma. The prognosis for IPF patients is poor and current therapies are largely ineffective in preventing...

  • Biomarkers: key to new therapies for IPF. Pinn, Stephen // British Journal of Hospital Medicine (17508460);Jan2014, Vol. 75 Issue 1, p11 

    The article focuses on the need to build better clinical trials and validate biomarkers of progression and treatment response for patients with idiopathic pulmonary fibrosis.

  • Therapeutic Potential of Modulating Natriuretic Peptides in Pulmonary Hypertension and Fibrosis. Hobbs, Adrian // Current Medical Literature: Pulmonary Hypertension;2012 Supplement, p13 

    The article focuses on a study on the significant role played by the modulation of natriuretic peptides (NPs) in the treatment of pulmonary hypertension (PH) and fibrosis. It notes that the study suggests that pulmonary vascular dysfunction which is one characteristic of pulmonary hypertension...

  • Growth factors in idiopathic pulmonary fibrosis: relative roles. Allen, Jeremy T.; Spiteri, Monica A. // Respiratory Research;2002, Vol. 3, p13 

    Treatment of idiopathic pulmonary fibrosis patients has evolved very slowly; the fundamental approach of corticosteroids alone or in combination with other immunosuppressive agents has had little impact on long-term survival. The continued use of corticosteroids is justified because of the lack...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics