Developmental pattern of 3-oxo-Δ4 bile acids in neonatal bile acid metabolism

Inoue, Toshiro; Kimura, Akihiko; Aoki, Kumiko; Tohma, Masahiko; Kato, Hirohisa
July 1997
Archives of Disease in Childhood -- Fetal & Neonatal Edition;Jul1997, Vol. 77 Issue 1, pF52
Academic Journal
No abstract available.


Related Articles

  • Diagnosis of the first Japanese patient with 3-oxo-delta4-steroid 5beta-reductase deficiency by use of immunoblot analysis. Kimura, A.; Kondo, K.-H.; Okuda, K.-I.; Higashi, S.; Suzuki, M.; Kurosawa, T.; Tohma, M.; Inoue, T.; Nishiyori, A.; Yoshino, M.; Kato, H.; Setoguchi, T. // European Journal of Pediatrics;1998, Vol. 157 Issue 5, p386 

    Unlabelled: A 3-oxo-delta4-steroid 5beta-reductase (5beta-reductase) deficiency is difficult to diagnose because severe liver damage can result in a similar pattern of metabolite excretion. We investigated the usefulness of immunoblot analysis for diagnosis of 5beta-reductase...

  • Bile Acid Signaling in Liver Metabolism and Diseases. Tiangang Li; Chiang, John Y. L. // Journal of Lipids;2012, p1 

    Obesity, diabetes, and metabolic syndromes are increasingly recognized as health concerns worldwide. Overnutrition and insulin resistance are the major causes of diabetic hyperglycemia and hyperlipidemia in humans. Studies in the past decade provide evidence that bile acids are not just...

  • Research progress in roles of gut microbiota and bile acid metabolism in development and progression of NAFLD. LU Xu; HAN Tao; TIAN Yao // Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi;nov2014, Vol. 30 Issue 11, p1225 

    With the prevalence of obesity and metabolic syndrome, the incidence of nonalcoholic fatty liver disease (NAFLD) is increasing year by year. Studies have uncovered the important roles of gut microbiota and bile acid metabolism in the development and progression of NAFLD. The roles of gut...

  • Metabolic Effects of Bile Acids in the Gut in Health and Disease. Boesjes, Marije; Brufau, Gemma // Current Medicinal Chemistry;Aug2014, Vol. 21 Issue 24, p2822 

    In the last decade, it became clear that bile acids, in addition to their role in intestinal absorption of lipids and fat-soluble vitamins, are major regulators of metabolism. They activate signal transduction pathways through binding to the specific bile acid receptors TGR5 and FXR. Indirectly,...

  • Bile Acid Sequestrants and the Treatment of Type 2 Diabetes Mellitus. Staels, Bart; Kuipers, Folkert // Drugs;2007, Vol. 67 Issue 10, p1383 

    Bile acids promote bile formation and facilitate dietary lipid absorption. Animal and human studies showing disturbed bile acid metabolism in diabetes mellitus suggest a link between bile acids and glucose control. Bile acids are activating ligands of the farnesoid X receptor (FXR), a nuclear...

  • Analysis of Bile Acids in Urine Specimens from Healthy Humans: Determination of Several Bile Acids with β-Hydroxyl and Carbonyl Groups. Yamaga, Nobuo; Ikebuchi, Jun; Kohara, Hiromi; Ogura, Yoshio; Yamada, Kazuo // Journal of Biochemistry;1996, Vol. 119 Issue 4, p725 

    Urinary bile acids of 39 healthy male undergraduates were analyzed by capillary gas chromatography and capillary gas chromatography-mass spectrometry. 3α-Hydroxy-12-oxo-5β-cholanoic acid, 3α,12β-dihydroxy-5β-cholanoic acid, 3β,7α-dihydroxy-5β-cholan-oic acid, and...

  • Bile Acids: Chemistry, Pathochemistry, Biology, Pathobiology, and Therapeutics. Hofmann, A.; Hagey, L. // Cellular & Molecular Life Sciences;Aug2008, Vol. 65 Issue 16, p2461 

    Bile acids and bile alcohols in the form of their conjugates are amphipathic end products of cholesterol metabolism with multiple physiological functions. The great variety of bile acids and bile alcohols that are present in vertebrates are tabulated. Bile salts have an enterohepatic circulation...

  • Effect of enterocoated cholestyramine on bowel habit after ileal resection: a double blind crossover study. Jacobsen, Oli; Hojgaard, Liselotte; Moller, Ellinor Hylander; Wielandt, Torben O.; Thale, Margrethe; Jarnum, Stig; Krag, Einar // British Medical Journal (Clinical Research Edition);5/4/1985, Vol. 290 Issue 6478, p1315 

    Examines the effects of enterocoated cholestyramine on bowel habit after ileal resection. Malabsorption of bile acid due to ileal resection; Reduction of diarrhea by cholestyramine; Effect of the drug on the metabolism of bile acid.

  • Bile Acid Metabolism in Health and Disease. Taylor, D. E. M. // Journal of the Royal Society of Medicine;Apr1978, Vol. 71 Issue 4, p313 

    The article reviews the book "Bile Acid Metabolism in Health and Disease," edited by G. Paumgartner and A. Stiehl.

  • Genetics of familial intrahepatic cholestasis syndromes. van Mil, S. W. C.; Houwen, R. H. J.; Klomp, L. W. J. // Journal of Medical Genetics;Jun2005, Vol. 42 Issue 6, p449 

    Bile acids and bile salts have essential functions in the liver and in the small intestine. Their synthesis in the liver provides a metabolic pathway for the catabolism of cholesterol and their detergent properties promote the solubilisation of essential nutrients and vitamins in the small...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics