TITLE

Mycobacterium bovis genotypes in Northern Ireland: herd-level surveillance (2003 to 2008)

AUTHOR(S)
Skuce, R. A.; Mallon, T. R.; McCormick, C. M.; McBride, S. H.; Clarke, G.; Thompson, A.; Couzens, C.; Gordon, A. W.; McDowell, S. W. J.
PUB. DATE
October 2010
SOURCE
Veterinary Record: Journal of the British Veterinary Association;Oct2010, Vol. 167 Issue 18, p684
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Surveillance genotyping (variable number tandem repeat profiling and spoligotyping) of isolates from culture-confirmed bovine tuberculosis (TB)-affected herds in Northern Ireland is presented for the years 2003 to 2008 inclusive. A total of 175 genotypes were identified in 8630 isolates from 6609 herds. On average, 73 genotypes were identified each year, with 29 genotypes present in all six years. Highly significant differences (P<0.0001) were observed between the relative frequency of some genotypes in the years 2003 to 2008. The spatial distribution of genotypes was not random (P<0.0001). Significant geographical localisation of genotypes was evident, suggesting that sources tended to be local. Despite regions being dominated by geographically localised genotypes, substantial and exploitable local diversity was still evident. Genotypes were also translocated significant distances from their normal geographical location.
ACCESSION #
66290829

 

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