- GLUT2 Accumulation in Enterocyte Apical and Intracellular Membranes. Ait-Omar, Amal; Monteiro-Sepulveda, Milena; Poitou, Christine; Le Gall, Maude; Cotillard, Aurélie; Gilet, Jules; Garbin, Kevin; Houllier, Anne; Château, Danièle; Lacombe, Amélie; Veyrie, Nicolas; Hugol, Danielle; Tordjman, Joan; Magnan, Christophe; Serradas, Patricia; Clément, Karine; Leturque, Armelle; Brot-Laroche, Edith // Diabetes;Oct2011, Vol. 60 Issue 10, p2598
OBJECTIVE-In healthy rodents, intestinal sugar absorption in response to sugar-rich meals and insulin is regulated by GLUT2 in enterocyte plasma membranes. Loss of insulin action maintains apical GLUT2 location. In human enterocytes, apical GLUT2 location has not been reported but may be...
- somatotropin. // Taber's Cyclopedic Medical Dictionary;2005, p2026
A definition of the term "somatotropin" is presented. It refers to the human growth hormone. It increases the rate of cell division and protein synthesis in growing tissues, mobilizes stored fats, and limits glucose production.
- Coordinated improvement in glucose tolerance, liver steatosis and obesity-associated inflammation by cannabinoid 1 receptor antagonism in fat Aussie mice. Bell-Anderson, K S; Aouad, L; Williams, H; Sanz, F R; Phuyal, J; Larter, C Z; Farrell, G C; Caterson, I D // International Journal of Obesity;Dec2011, Vol. 35 Issue 12, p1539
Objective:Fat Aussie mice (foz/foz) are morbidly obese, glucose intolerant and have liver steatosis that develops into steatohepatitis on a high-fat diet. The cannabinoid 1 receptor (CB1) antagonist SR141716 has been shown to improve obesity-associated metabolic complications in humans and...
- High saturated-fat diet induces apoptosis in rat enterocytes and blunts GIP and insulin-secretive response to oral glucose load. Gniuli, D.; Libera, L. Dalla; Caristo, M. E.; Calvani, R.; Castagneto, M.; Mingrone, G. // International Journal of Obesity;May2008, Vol. 32 Issue 5, p871
Lipoapoptosis has been described in many organs and tissues, but never in enterocytes. We hypothesized that a high saturated-fat diet can induce duodenal enterocyte apoptosis and impair gastric inhibitory polypeptide (GIP) secretion. Forty male Wistar rats, âˆ¼4 months old, were randomized on...
- Insulin Internalizes GLUT2 in the Enterocytes of Healthy but Not Insulin-Resistant Mice. Tobin, Vanessa; Le Gall, Maude; Fioramonti, Xavier; Stolarczyk, Emilie; Blazquez, Alba G.; Klein, Christophe; Prigent, Magali; Serradas, Patricia; Cuif, Marie-Hélène; Magnan, Christophe; Leturque, Armelle; Brot-Laroche, Edith // Diabetes;Mar2008, Vol. 57 Issue 3, p555
OBJECTIVES--A physiological adaptation to a sugar-rich meal is achieved by increased sugar uptake to match dietary load, resulting from a rapid transient translocation of the fructose/ glucose GLUT2 transporter to the brush border membrane (BBM) of enterocytes. The aim of this study was to...
- Role of heparan sulfate in interactions of Listeria monocytogenes with enterocytes. Henry-Stanley, Michelle J.; Hess, Donavon J.; Erickson, Elizabeth A.; Garni, Robb M.; Wells, Carol L. // Medical Microbiology & Immunology;May2003, Vol. 192 Issue 2, p107
Heparan sulfate is known to participate in binding a wide variety of microbes to mammalian cells, but few studies have focused on the enterocyte. Normal human colonic and small intestinal enterocytes, and cultured HT-29 (but not Caco-2) enterocytes, reacted prominently with antibodies specific...
- Short-Term High-Fat Diet Alters Substrate Utilization During Exercise But Not Glucose Tolerance in Highly Trained Athletes. Staudacher, Heidi M.; Carey, Andrew L.; Cummings, Nicola K.; Hawley, John A.; Burke, Louise M. // International Journal of Sport Nutrition & Exercise Metabolism;Sep2001, Vol. 11 Issue 3, p273
Determines the effect of a high-fat diet and carbohydrate restoration on substrate oxidation and glucose tolerance in competitive ultra-endurance athletes. Rates of substrate oxidation; Changes in oral glucose tolerance; Rates of substrate utilization.
- Increase in Insulin Action and Fat Oxidation After Treatment With CL 316,243, a Highly Selective beta[sub 3]-Adrenoceptor Agonist in Humans. Weyer, Christian; Tataranni, P. Antonio; Snitker, Soren; Danforth Jr., Elliot; Ravussin, Eric // Diabetes;Oct1998, Vol. 47 Issue 10, p1555
Assesses the effects of a selective beta3-adrenoceptor agonist on insulin action and fat oxidation in humans. Determination of fat oxidation rates; Use of H-glucose infusion methods to determine splanchnic glucose output rates; Analysis of plasma glucose through glucose oxidase methods.
- Fat: The vital statistics. Thomson, Janet // 28 Days to a Better Body;1997, p52
Chapter 4. Discusses the benefits and liabilities of the use of fat by the human body. Differences between polyunsaturated and monounsaturated fats; How the body stores fat.
- Eat to beat diabetes. Levine, Hallie // All You;4/23/2010, Vol. 7 Issue 4, p54
The article discusses various issues related to human health as of April 2010. It defines diabetes as a common disease form resulting from glucose buildup in the blood because the body cannot store glucose in the fat and muscles. The author also mentions the lifestyle changes that people can do...