Excitotoxic amino acid neurotransmitters are increased in human cerebrospinal fluid after subarachnoid haemorrhage

Kashiwagi, S; Fujisawa, H; Yamashita, T; Ito, H; Maekawa, T; Kuroda, Y; Tateishi, A
November 1994
Journal of Neurology, Neurosurgery & Psychiatry;Nov1994, Vol. 57 Issue 11, p1442
Academic Journal
No abstract available.


Related Articles

  • Accurate diagnosis of subarachnoid haemorrhage. McCarron, Mark O; O’Kane, Maurice J // Annals of Clinical Biochemistry;Nov2014, Vol. 51 Issue 6, p629 

    An introduction to the journal is presented in which the editors discuss the importance of cerebrospinal fluid (CSF) spectrophotometry in the accurate diagnosis of subarachnoid haemorrhage (SAH).

  • Specificity of elevated cerebrospinal fluid bilirubin in the investigation of subarachnoid haemorrhage. Walker, Susan A; Peter Ashby, J; Falconer, Helen L // Annals of Clinical Biochemistry;May2015, Vol. 52 Issue 3, p404 

    Background: The spectrophotometric examination of cerebrospinal fluid for bilirubin is an established investigation in patients with suspected subarachnoid haemorrhage. This study assesses the diagnostic specificity of an elevated cerebrospinal fluid bilirubin and how this may be influenced by...

  • Analysis of cerebrospinal fluid for xanthochromia versus modern computed tomography scanners in the diagnosis of subarachnoid haemorrhage: experience at a tertiary trauma referral centre. Goyale, A.; O’Shea, J.; Marsden, J.; Keep, J.; Vincent, R. P.; O'Shea, J // Annals of Clinical Biochemistry;Jan2016, Vol. 53 Issue 1, p150 

    Background: Diagnosis of subarachnoid haemorrhage, a neurosurgical emergency in patients with headache remains a logistical challenge. The rationale of the traditional pathway of cerebrospinal fluid xanthochromia analysis following negative computed tomography head scans to exclude...

  • EXCITOTOXICITY AND CELL DAMAGE - A REVIEW. Shaikh, Saba; Dubey, Ravi; Joshi, Y. M.; Kadam, Vilasrao J. // International Journal of Pharmaceutical Sciences & Research;Jun2013, Vol. 4 Issue 6, p2062 

    Excitotoxicity refers to the pathological process by which nerve cells are damaged & killed by glutamate or related excitatory amino acid under conditions such as after intense exposure. This occurs when receptor for the excitatory neurotransmitter such as N-methyl-D-aspartate (NMDA) or AMPA are...

  • GLOSSARY.  // Equus;Aug2014, Issue 443, p71 

    A glossary of biological terms including amino acids, neurotransmitters and synovial fluid is presented.

  • Aneurysmal subarachnoid haemorrhage: guidance in making the correct diagnosis. Liebenberg, W. A.; Worth, R.; Firth, G. B.; Olney, J.; Norris, J. S. // Postgraduate Medical Journal;Jul2005, Vol. 81 Issue 957, p470 

    Background: The natural history of untreated aneurysmal subarachnoid haemorrhage carries a dismal prognosis. Case fatalities range between 32% and 67%. Treatment with either surgical clipping or endovascular coiling is highly successful at preventing re-bleeding and yet the diagnosis is still...

  • A Role for Excitatory Amino Acids in Diabetic Eye Disease. Pulido, Jose E.; Pulido, Jose S.; Erie, Jay C.; Arroyo, Jorge; Bertram, Kurt; Miao-Jen Lu; Shippy, Scott A. // Experimental Diabetes Research;2007, p1 

    Diabetic retinopathy is a leading cause of vision loss. The primary clinical hallmarks are vascular changes that appear to contribute to the loss of sight. In a number of neurodegenerative disorders there is an appreciation that increased levels of excitatory amino acids are excitotoxic. The...

  • An amino acid mixture deficient in phenylalanine and tyrosine reduces cerebrospinal fluid catecholamine metabolites and alcohol consumption in vervet monkeys. Palmour, R. M.; Ervin, Frank R.; Baker, Glen B.; Young, Simon N. // Psychopharmacology;1998, Vol. 136 Issue 1, p1 

    Abstract An amino acid mixture devoid of tryptophan, given orally, was previously shown to reduce cerebrospinal fluid levels of tryptophan and 5-hydroxyindoleacetic acid in vervet monkeys, as compared to a control mixture containing all essential amino acids. In the present study, we tested the...

  • Cerebral microdialysis as a new tool for neurometabolic monitoring. Peerdeman, S. M.; Girbes, A. R.J.; Vandertop, W. P. // Intensive Care Medicine;Jun2000, Vol. 26 Issue 6, p662 

    Describes the cerebral microdialysis technique and its current applications. Correlations between clinical events such as high intracranial pressure and low CPP and high lactate, low glucose, high excitatory amino acids and anti-oxidant concentrations in the extracellular fluid; Relationship...

  • Revised national guidelines for the analysis of cerebrospinal fluid for bilirubin in suspected subarachnoid haemorrhage. Absalom, S. R. // Annals of Clinical Biochemistry;Mar2009, Vol. 46 Issue 2, p177 

    A letter to the editor is presented in response to the article "Revised National Guidelines for Analysis of Cerebrospinal Fluid for Bilirubin in Suspected Subarachnoid Haemorrhage," by Anne Cruickshank and colleagues published in a previous issue of the journal.


Read the Article


Sign out of this library

Other Topics