Effect of azelastine on bronchoconstriction induced by histamine and leukotriene C4 in patients with extrinsic asthma

Albazzaz, M K; Patel, K R
April 1988
Thorax;Apr1988, Vol. 43 Issue 4, p306
Academic Journal
No abstract available.


Related Articles

  • Atropine, Sodium Cromoglycate, and Thymoxamine in PGF[sub2] alpha-induced Bronchoconstriction in Extrinsic Asthma . Patel, K.R. // British Medical Journal;5/17/1975, Vol. 2 Issue 5967, p360 

    Examines the effect of prostaglandin inhalation in patients with extrinsic bronchial asthma in Great Britain. Emphasis on bronchoconstriction incidence; Assessment on the release of prostaglandin; Clinical manifestations of bronchoconstriction.

  • RoIe of cysteinyl leukotrienes in adenosine 5' -monophosphate induced bronchoconstriction in asthma. Rorke, S.; Jennison, S.; Jeffs, J. A.; Sampson, A. P.; Arshad, H.; Holgate, S. T. // Thorax;Apr2002, Vol. 57 Issue 4, p323 

    Background: Adenosine induced bronchoconstriction in patients with asthma is thought to be mediated by the synthesis and release of autacoids from airway mast cells. In vitro, adenosine induced constriction of asthmatic bronchi is blocked by a combination of specific histamine and cysteinyl...

  • The Effect of Inhaled Heparin on Airway Responsiveness to Histamine and Leukotriene D[sub4]. Stelmach, Iwona; Jerzynska, Joanna; Stelmach, Wlodzimierz; Majak, Pawel; Brzozowska, Agnieszka; Gorski, Pawel; Kuna, Piotr // Allergy & Asthma Proceedings;Jan/Feb2003, Vol. 24 Issue 1, p59 

    Inhaled heparin has been shown to reduce the early and late phase of asthmatic reactions and suppress an allergen-induced increase in bronchial hyperreactivity. The mechanism involved in the control of bronchial hyperreactivity in asthma by heparin is still not understood. The purpose of...

  • Effect of budesonide and azelastine on histamine signaling regulation in human nasal epithelial cells. Liu, Shao-Cheng; Lin, Chun-Shu; Chen, Shyi-Gen; Chu, Yueng-Hsiang; Lee, Fei-Peng; Lu, Hsuan-Hsuan; Wang, Hsing-Won // European Archives of Oto-Rhino-Laryngology;Feb2017, Vol. 274 Issue 2, p845 

    Both glucocorticoids and H1-antihistamines are widely used on patients with airway diseases. However, their direct effects on airway epithelial cells are not fully explored. Therefore, we use the primary culture of human nasal epithelial cells (HNEpC) to delineate in vitro mucosal responses to...

  • Histamine, But Not Leukotriene C4, is an Essential Mediator in Cold Urticaria Wheals. Nuut!Nen, Pauliina; Harvima, Ilkka T.; Ackermann, Leena // Acta Dermato-Venereologica;2007, Vol. 87 Issue 1, p9 

    In addition to histamine, leukotriene C4 (LTC4) might also play a role in mediating cold urticaria wheals. To study the significance of LTC4 vs. histamine, 6 patients with cold urticaria were challenged with the ice cube test before and after ingestion of 10 mg cetirizine (antihistamine), 10 mg...

  • Severe bronchoconstriction provoked by sodium cromoglycate. Paterson, Ian C.; Grant, Ian W.H.; Crompton, Graham K. // British Medical Journal;10/16/1976, Vol. 2 Issue 6041, p916 

    Presents a case study of a patient who developed severe bronchoconstriction after inhaling sodium cromoglycate (SCG). Effectiveness of SCG in the treatment of asthma; Reports on the allergic reactions to drugs; Observations on the cause of the SCG in asthma to the prevention of release of...

  • The causes of asthma -- does salt potentiate bronchial activity? discussion paper. Burney, P. G. J. // Journal of the Royal Society of Medicine;Jun1987, Vol. 80 Issue 6, p364 

    The article examines whether salt potentiates bronchial activity or asthma in particular. It mentions that the disease is prevalent between the highland and the more developed coastal populations in Papua New Guinea. Endogenous mediators like histamine, prostaglandins or leukotrienes and...

  • What best prevents exercise-induced bronchoconstriction for a child with asthma? Preston, Jeffrey; Cucuzzella, Mark; Jamieson, Barbara // Journal of Family Practice;Jul2006, Vol. 55 Issue 7, p631 

    The article provides information regarding the effective ways in preventing exercise-induced bronchoconstriction for a child with asthma. Inhaled short-acting beta-agonists are considered to be the most effective way in preventing exercise-induced bronchoconstriction, followed by inhaled mast...

  • Met-Enkephalin Effects on Histamine-Induced Bronchoconstriction in Guinea Pigs. Tješić-Drinković, Dorian; Štambuk, Nikola; Tješić-Drinković, Duška; Konjevoda, Paško; Gotovac, Nikola; Ćurković, Tihomir; Votava-Raić, Ana // Collegium Antropologicum;Dec2005, Vol. 29 Issue 2, p689 

    We investigated the effects of the neuropeptide met-enkephalin on histamine-induced bronhoconstriction in an experimental model of asthma. Classic Konzett and Rössler's method of whole body plethysmography modified by Gjuriš, was applied in the study. This method represents a standard...

  • Montelukast, A Leukotriene-Receptor Antagonist, for the Treatment of Mild Asthma and Exercise-Induced Bronchoconstriction. Lampe, John B.; McDowell, Karen M. // Clinical Pediatrics;Jan1999, Vol. 38 Issue 1, p60 

    Presents information on a study which examines montelukast, a leukotriene-receptor antagonist, for the treatment of mild asthma and exercise-induced bronchoconstriction. Methodology of the study; Results and discussion on the study; Comment on the study.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics